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Page 1
Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient.
Milione M, Ardini E, Christiansen J, Valtorta E, Veronese S, Bosotti R, Pellegrinelli A, Testi A, Pietrantonio F, Fucà G, Wei G, Murphy D, Siena S, Isacchi A, De Braud F. Milione M, et al. Among authors: isacchi a. Oncotarget. 2017 Jul 24;8(33):55353-55360. doi: 10.18632/oncotarget.19512. eCollection 2017 Aug 15. Oncotarget. 2017. PMID: 28903424 Free PMC article.
FAT: a novel domain in PIK-related kinases.
Bosotti R, Isacchi A, Sonnhammer EL. Bosotti R, et al. Among authors: isacchi a. Trends Biochem Sci. 2000 May;25(5):225-7. doi: 10.1016/s0968-0004(00)01563-2. Trends Biochem Sci. 2000. PMID: 10782091 No abstract available.
PoInTree: a polar and interactive phylogenetic tree.
Carreras M, Gianti E, Sartori L, Plyte SE, Isacchi A, Bosotti R. Carreras M, et al. Among authors: isacchi a. Genomics Proteomics Bioinformatics. 2005 Feb;3(1):58-60. doi: 10.1016/s1672-0229(05)03009-3. Genomics Proteomics Bioinformatics. 2005. PMID: 16144524 Free PMC article.
Transcriptional analysis of an E2F gene signature as a biomarker of activity of the cyclin-dependent kinase inhibitor PHA-793887 in tumor and skin biopsies from a phase I clinical study.
Locatelli G, Bosotti R, Ciomei M, Brasca MG, Calogero R, Mercurio C, Fiorentini F, Bertolotti M, Scacheri E, Scaburri A, Galvani A, Pesenti E, De Baere T, Soria JC, Lazar V, Isacchi A. Locatelli G, et al. Among authors: isacchi a. Mol Cancer Ther. 2010 May;9(5):1265-73. doi: 10.1158/1535-7163.MCT-09-1163. Epub 2010 Apr 27. Mol Cancer Ther. 2010. PMID: 20423997
Cell line identity finding by fingerprinting, an optimized resource for short tandem repeat profile authentication.
Somaschini A, Amboldi N, Nuzzo A, Scacheri E, Ukmar G, Ballinari D, Malyszko J, Raddrizzani L, Landonio A, Gasparri F, Galvani A, Isacchi A, Bosotti R. Somaschini A, et al. Among authors: isacchi a. Genet Test Mol Biomarkers. 2013 Mar;17(3):254-9. doi: 10.1089/gtmb.2012.0359. Epub 2013 Jan 28. Genet Test Mol Biomarkers. 2013. PMID: 23356232
The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
Ardini E, Bosotti R, Borgia AL, De Ponti C, Somaschini A, Cammarota R, Amboldi N, Raddrizzani L, Milani A, Magnaghi P, Ballinari D, Casero D, Gasparri F, Banfi P, Avanzi N, Saccardo MB, Alzani R, Bandiera T, Felder E, Donati D, Pesenti E, Sartore-Bianchi A, Gambacorta M, Pierotti MA, Siena S, Veronese S, Galvani A, Isacchi A. Ardini E, et al. Among authors: isacchi a. Mol Oncol. 2014 Dec;8(8):1495-507. doi: 10.1016/j.molonc.2014.06.001. Epub 2014 Jun 12. Mol Oncol. 2014. PMID: 24962792 Free PMC article.
Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
Sartore-Bianchi A, Ardini E, Bosotti R, Amatu A, Valtorta E, Somaschini A, Raddrizzani L, Palmeri L, Banfi P, Bonazzina E, Misale S, Marrapese G, Leone A, Alzani R, Luo D, Hornby Z, Lim J, Veronese S, Vanzulli A, Bardelli A, Martignoni M, Davite C, Galvani A, Isacchi A, Siena S. Sartore-Bianchi A, et al. Among authors: isacchi a. J Natl Cancer Inst. 2015 Nov 12;108(1):djv306. doi: 10.1093/jnci/djv306. Print 2016 Jan. J Natl Cancer Inst. 2015. PMID: 26563355 Free PMC article.
84 results