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Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.
Fankhauser M, Broggi MAS, Potin L, Bordry N, Jeanbart L, Lund AW, Da Costa E, Hauert S, Rincon-Restrepo M, Tremblay C, Cabello E, Homicsko K, Michielin O, Hanahan D, Speiser DE, Swartz MA. Fankhauser M, et al. Among authors: hanahan d. Sci Transl Med. 2017 Sep 13;9(407):eaal4712. doi: 10.1126/scitranslmed.aal4712. Sci Transl Med. 2017. PMID: 28904226 Clinical Trial.
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, Ostos LC, Lannon WA, Grotzinger C, Del Rio M, Lhermitte B, Olshen AB, Wiedenmann B, Cantley LC, Gray JW, Hanahan D. Sadanandam A, et al. Among authors: hanahan d. Nat Med. 2013 May;19(5):619-25. doi: 10.1038/nm.3175. Epub 2013 Apr 14. Nat Med. 2013. PMID: 23584089 Free PMC article.
Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression.
Saghafinia S, Homicsko K, Di Domenico A, Wullschleger S, Perren A, Marinoni I, Ciriello G, Michael IP, Hanahan D. Saghafinia S, et al. Among authors: hanahan d. Cancer Discov. 2021 Oct;11(10):2638-2657. doi: 10.1158/2159-8290.CD-20-1637. Epub 2021 Apr 28. Cancer Discov. 2021. PMID: 33910926 Free PMC article.
Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion.
Zeng Q, Saghafinia S, Chryplewicz A, Fournier N, Christe L, Xie YQ, Guillot J, Yucel S, Li P, Galván JA, Karamitopoulou E, Zlobec I, Ataca D, Gallean F, Zhang P, Rodriguez-Calero JA, Rubin M, Tichet M, Homicsko K, Hanahan D. Zeng Q, et al. Among authors: hanahan d. Science. 2022 Nov 18;378(6621):eabl7207. doi: 10.1126/science.abl7207. Epub 2022 Nov 18. Science. 2022. PMID: 36395212
430 results