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Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW. Schonhoft JD, et al. Among authors: plate l. Sci Transl Med. 2017 Sep 13;9(407):eaam7621. doi: 10.1126/scitranslmed.aam7621. Sci Transl Med. 2017. PMID: 28904227 Free PMC article.
BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels.
Han D, Schaffner SH, Davies JP, Benton ML, Plate L, Nordman JT. Han D, et al. Among authors: plate l. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2305092120. doi: 10.1073/pnas.2305092120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722046 Free PMC article.
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.
Hazari Y, Urra H, Garcia Lopez VA, Diaz J, Tamburini G, Milani M, Pihan P, Durand S, Aprahamia F, Baxter R, Huang M, Dong XC, Vihinen H, Batista-Gonzalez A, Godoy P, Criollo A, Ratziu V, Foufelle F, Hengstler JG, Jokitalo E, Bailly-Maitre B, Maiers JL, Plate L, Kroemer G, Hetz C. Hazari Y, et al. Among authors: plate l. bioRxiv [Preprint]. 2023 May 2:2023.05.02.538835. doi: 10.1101/2023.05.02.538835. bioRxiv. 2023. PMID: 37205565 Free PMC article. Preprint.
ATF6 protects against protein misfolding during cardiac hypertrophy.
Hofmann C, Aghajani M, Alcock CD, Blackwood EA, Sandmann C, Herzog N, Groß J, Plate L, Wiseman RL, Kaufman RJ, Katus HA, Jakobi T, Völkers M, Glembotski CC, Doroudgar S. Hofmann C, et al. Among authors: plate l. J Mol Cell Cardiol. 2024 Apr;189:12-24. doi: 10.1016/j.yjmcc.2024.02.001. Epub 2024 Feb 23. J Mol Cell Cardiol. 2024. PMID: 38401179
The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue.
Egly CL, Barny L, Do T, McDonald EF, Plate L, Knollmann BC. Egly CL, et al. Among authors: plate l. bioRxiv [Preprint]. 2024 Jan 31:2024.01.31.574410. doi: 10.1101/2024.01.31.574410. bioRxiv. 2024. Update in: J Biol Chem. 2024 Jul;300(7):107465. doi: 10.1016/j.jbc.2024.107465 PMID: 38352392 Free PMC article. Updated. Preprint.
95 results