Muthumani K - Search Results

1

An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.

Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB. Patel A, et al. Among authors: muthumani k. Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7. Nat Commun. 2017. PMID: 28935938 Free PMC article.

2

Vpr-GFP virion particle identifies HIV-infected targets and preserves HIV-1Vpr function in macrophages and T-cells.

Muthumani K, Montaner LJ, Ayyavoo V, Weiner DB. Muthumani K, et al. DNA Cell Biol. 2000 Mar;19(3):179-88. doi: 10.1089/104454900314564. DNA Cell Biol. 2000. PMID: 10749170

3

Inclusion of Vpr accessory gene in a plasmid vaccine cocktail markedly reduces Nef vaccine effectiveness in vivo resulting in CD4 cell loss and increased viral loads in rhesus macaques.

Muthumani K, Bagarazzi M, Conway D, Hwang DS, Ayyavoo V, Zhang D, Manson K, Kim J, Boyer J, Weiner DB. Muthumani K, et al. J Med Primatol. 2002 Aug;31(4-5):179-85. doi: 10.1034/j.1600-0684.2002.02004.x. J Med Primatol. 2002. PMID: 12390540

4

Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism.

Muthumani K, Choo AY, Premkumar A, Hwang DS, Thieu KP, Desai BM, Weiner DB. Muthumani K, et al. Cell Death Differ. 2005 Aug;12 Suppl 1:962-70. doi: 10.1038/sj.cdd.4401583. Cell Death Differ. 2005. PMID: 15832179 Review.

5

Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo.

Kutzler MA, Kraynyak KA, Nagle SJ, Parkinson RM, Zharikova D, Chattergoon M, Maguire H, Muthumani K, Ugen K, Weiner DB. Kutzler MA, et al. Among authors: muthumani k. Gene Ther. 2010 Jan;17(1):72-82. doi: 10.1038/gt.2009.112. Epub 2009 Oct 22. Gene Ther. 2010. PMID: 19847203 Free PMC article.

6

Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination.

Fagone P, Shedlock DJ, Bao H, Kawalekar OU, Yan J, Gupta D, Morrow MP, Patel A, Kobinger GP, Muthumani K, Weiner DB. Fagone P, et al. Among authors: muthumani k. Gene Ther. 2011 Nov;18(11):1070-7. doi: 10.1038/gt.2011.59. Epub 2011 May 5. Gene Ther. 2011. PMID: 21544096 Free PMC article.

7

Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab.

Muthumani K, Flingai S, Wise M, Tingey C, Ugen KE, Weiner DB. Muthumani K, et al. Hum Vaccin Immunother. 2013 Oct;9(10):2253-62. doi: 10.4161/hv.26498. Epub 2013 Sep 17. Hum Vaccin Immunother. 2013. PMID: 24045230 Free PMC article.

8

Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants.

Flingai S, Czerwonko M, Goodman J, Kudchodkar SB, Muthumani K, Weiner DB. Flingai S, et al. Among authors: muthumani k. Front Immunol. 2013 Nov 4;4:354. doi: 10.3389/fimmu.2013.00354. Front Immunol. 2013. PMID: 24204366 Free PMC article. Review.

9

HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo.

Muthumani K, Wise MC, Broderick KE, Hutnick N, Goodman J, Flingai S, Yan J, Bian CB, Mendoza J, Tingey C, Wilson C, Wojtak K, Sardesai NY, Weiner DB. Muthumani K, et al. PLoS One. 2013 Dec 31;8(12):e84234. doi: 10.1371/journal.pone.0084234. eCollection 2013. PLoS One. 2013. PMID: 24391921 Free PMC article.

10

Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.

Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, Weiner DB. Yan J, et al. Among authors: muthumani k, muthumani a. Cancer Gene Ther. 2014 Dec;21(12):507-17. doi: 10.1038/cgt.2014.56. Epub 2014 Nov 14. Cancer Gene Ther. 2014. PMID: 25394503

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