Egli M - Search Results

1

4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.

Malek-Adamian E, Guenther DC, Matsuda S, Martínez-Montero S, Zlatev I, Harp J, Burai Patrascu M, Foster DJ, Fakhoury J, Perkins L, Moitessier N, Manoharan RM, Taneja N, Bisbe A, Charisse K, Maier M, Rajeev KG, Egli M, Manoharan M, Damha MJ. Malek-Adamian E, et al. Among authors: egli m. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555. doi: 10.1021/jacs.7b07582. Epub 2017 Oct 6. J Am Chem Soc. 2017. PMID: 28937776

2

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: egli m. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

3

Internal derivatization of oligonucleotides with selenium for X-ray crystallography using MAD.

Du Q, Carrasco N, Teplova M, Wilds CJ, Egli M, Huang Z. Du Q, et al. Among authors: egli m. J Am Chem Soc. 2002 Jan 9;124(1):24-5. doi: 10.1021/ja0171097. J Am Chem Soc. 2002. PMID: 11772055

4

2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.

Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M. Prakash TP, et al. Among authors: egli m. Biochemistry. 2002 Oct 1;41(39):11642-8. doi: 10.1021/bi020264t. Biochemistry. 2002. PMID: 12269806

5

Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA.

Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Wilds CJ, et al. Among authors: egli m. J Am Chem Soc. 2002 Nov 20;124(46):13716-21. doi: 10.1021/ja0207807. J Am Chem Soc. 2002. PMID: 12431101

6

Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure.

Wilds CJ, Pattanayek R, Pan C, Wawrzak Z, Egli M. Wilds CJ, et al. Among authors: egli m. J Am Chem Soc. 2002 Dec 18;124(50):14910-6. doi: 10.1021/ja021058b. J Am Chem Soc. 2002. PMID: 12475332

7

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

8

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects.

Prhavc M, Prakash TP, Minasov G, Cook PD, Egli M, Manoharan M. Prhavc M, et al. Among authors: egli m. Org Lett. 2003 Jun 12;5(12):2017-20. doi: 10.1021/ol0340991. Org Lett. 2003. PMID: 12790517

9

2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures.

Prakash TP, Püschl A, Lesnik E, Mohan V, Tereshko V, Egli M, Manoharan M. Prakash TP, et al. Among authors: egli m. Org Lett. 2004 Jun 10;6(12):1971-4. doi: 10.1021/ol049470e. Org Lett. 2004. PMID: 15176796

10

Water-nucleobase "stacking": H-pi and lone pair-pi interactions in the atomic resolution crystal structure of an RNA pseudoknot.

Sarkhel S, Rich A, Egli M. Sarkhel S, et al. Among authors: egli m. J Am Chem Soc. 2003 Jul 30;125(30):8998-9. doi: 10.1021/ja0357801. J Am Chem Soc. 2003. PMID: 15369340

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