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Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.
Cruchaga C, Del-Aguila JL, Saef B, Black K, Fernandez MV, Budde J, Ibanez L, Deming Y, Kapoor M, Tosto G, Mayeux RP, Holtzman DM, Fagan AM, Morris JC, Bateman RJ, Goate AM; Dominantly Inherited Alzheimer Network (DIAN); Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study; Harari O. Cruchaga C, et al. Among authors: holtzman dm. Alzheimers Dement. 2018 Feb;14(2):205-214. doi: 10.1016/j.jalz.2017.08.013. Epub 2017 Sep 21. Alzheimers Dement. 2018. PMID: 28943286 Free PMC article.
Molecular studies in Alzheimer's disease.
Holtzman DM, Mobley WC. Holtzman DM, et al. Trends Biochem Sci. 1991 Apr;16(4):140-4. doi: 10.1016/0968-0004(91)90056-2. Trends Biochem Sci. 1991. PMID: 1877089 Review.
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