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Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.
Cruchaga C, Del-Aguila JL, Saef B, Black K, Fernandez MV, Budde J, Ibanez L, Deming Y, Kapoor M, Tosto G, Mayeux RP, Holtzman DM, Fagan AM, Morris JC, Bateman RJ, Goate AM; Dominantly Inherited Alzheimer Network (DIAN); Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study; Harari O. Cruchaga C, et al. Among authors: tosto g. Alzheimers Dement. 2018 Feb;14(2):205-214. doi: 10.1016/j.jalz.2017.08.013. Epub 2017 Sep 21. Alzheimers Dement. 2018. PMID: 28943286 Free PMC article.
Genetic admixture predictors of fetal alcohol spectrum disorders (FASD) in the South African Cape Coloured population.
Carter RC, Yang Z, Akkaya-Hocagil T, Jacobson SW, Jacobson JL, Dodge NC, Hoyme HE, Zeisel SH, Meintjes EM, Kizil C, Tosto G. Carter RC, et al. Among authors: tosto g. medRxiv [Preprint]. 2024 Apr 1:2024.03.31.24305130. doi: 10.1101/2024.03.31.24305130. medRxiv. 2024. Update in: Gene. 2024 Dec 30;931:148854. doi: 10.1016/j.gene.2024.148854. PMID: 38633769 Free PMC article. Updated. Preprint.
Country Level Incidence of Alzheimer Disease and Related Dementias is Associated with Increased Omega6 PUFA Consumption.
Ciesielski TH, Tosto G, Durodoye RO, Rajabali F, Akinyemi RO, Byrd GS, Bush WS, Kunkle BW, Reitz C, Vance JM, Pericak-Vance MA, Haines JL, Williams SM. Ciesielski TH, et al. Among authors: tosto g. medRxiv [Preprint]. 2024 Aug 8:2024.08.07.24311637. doi: 10.1101/2024.08.07.24311637. medRxiv. 2024. PMID: 39148832 Free PMC article. Preprint.
A Specialized Reference Panel with Structural Variants Integration for Improving Genotype Imputation in Alzheimer's Disease and Related Dementias (ADRD).
Cheng PL, Wang H, Dombroski BA, Farrell JJ, Horng I, Chung T, Tosto G, Kunkle BW, Bush WS, Vardarajan B, Schellenberg GD, Lee WP. Cheng PL, et al. Among authors: tosto g. medRxiv [Preprint]. 2024 Jul 23:2024.07.22.24310827. doi: 10.1101/2024.07.22.24310827. medRxiv. 2024. PMID: 39108532 Free PMC article. Preprint.
White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment.
Guzman VA, Carmichael OT, Schwarz C, Tosto G, Zimmerman ME, Brickman AM; Alzheimer's Disease Neuroimaging Initiative. Guzman VA, et al. Among authors: tosto g. Alzheimers Dement. 2013 Oct;9(5 Suppl):S124-31. doi: 10.1016/j.jalz.2012.11.009. Epub 2013 Jan 30. Alzheimers Dement. 2013. PMID: 23375566 Free PMC article.
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R; Alzheimer's Disease Genetics Consortium (ADGC). Reitz C, et al. Among authors: tosto g. Transl Psychiatry. 2013 May 14;3(5):e256. doi: 10.1038/tp.2013.13. Transl Psychiatry. 2013. PMID: 23673467 Free PMC article.
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