Cochran JR - Search Results

1

Heterochiral Knottin Protein: Folding and Solution Structure.

Mong SK, Cochran FV, Yu H, Graziano Z, Lin YS, Cochran JR, Pentelute BL. Mong SK, et al. Among authors: cochran fv, cochran jr. Biochemistry. 2017 Oct 31;56(43):5720-5725. doi: 10.1021/acs.biochem.7b00722. Epub 2017 Oct 17. Biochemistry. 2017. PMID: 28952732 Free PMC article.

2

Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity.

Kimura RH, Levin AM, Cochran FV, Cochran JR. Kimura RH, et al. Among authors: cochran fv, cochran jr. Proteins. 2009 Nov 1;77(2):359-69. doi: 10.1002/prot.22441. Proteins. 2009. PMID: 19452550 Free PMC article.

3

Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein.

Lahti JL, Silverman AP, Cochran JR. Lahti JL, et al. Among authors: cochran jr. PLoS Comput Biol. 2009 Sep;5(9):e1000499. doi: 10.1371/journal.pcbi.1000499. Epub 2009 Sep 4. PLoS Comput Biol. 2009. PMID: 19730675 Free PMC article.

4

A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging.

Jiang H, Moore SJ, Liu S, Liu H, Miao Z, Cochran FV, Liu Y, Tian M, Cochran JR, Zhang H, Cheng Z. Jiang H, et al. Among authors: cochran fv, cochran jr. Amino Acids. 2013 Feb;44(2):673-81. doi: 10.1007/s00726-012-1391-y. Epub 2012 Sep 4. Amino Acids. 2013. PMID: 22945905

5

A chemically cross-linked knottin dimer binds integrins with picomolar affinity and inhibits tumor cell migration and proliferation.

Kim JW, Cochran FV, Cochran JR. Kim JW, et al. Among authors: cochran fv, cochran jr. J Am Chem Soc. 2015 Jan 14;137(1):6-9. doi: 10.1021/ja508416e. Epub 2014 Dec 22. J Am Chem Soc. 2015. PMID: 25486381 Free PMC article.

6

Structural Basis of the Differential Binding of Engineered Knottins to Integrins αVβ3 and α5β1.

Van Agthoven JF, Shams H, Cochran FV, Alonso JL, Kintzing JR, Garakani K, Adair BD, Xiong JP, Mofrad MRK, Cochran JR, Arnaout MA. Van Agthoven JF, et al. Among authors: cochran fv, cochran jr. Structure. 2019 Sep 3;27(9):1443-1451.e6. doi: 10.1016/j.str.2019.06.011. Epub 2019 Jul 25. Structure. 2019. PMID: 31353240 Free PMC article.

7

Identification of N-Terminally Diversified GLP-1R Agonists Using Saturation Mutagenesis and Chemical Design.

Longwell CK, Hanna S, Hartrampf N, Sperberg RAP, Huang PS, Pentelute BL, Cochran JR. Longwell CK, et al. Among authors: cochran jr. ACS Chem Biol. 2021 Jan 15;16(1):58-66. doi: 10.1021/acschembio.0c00722. Epub 2020 Dec 14. ACS Chem Biol. 2021. PMID: 33307682 Free PMC article.

8

Elucidation of the interleukin-15 binding site on its alpha receptor by NMR.

Hanick NA, Rickert M, Varani L, Bankovich AJ, Cochran JR, Kim DM, Surh CD, Garcia KC. Hanick NA, et al. Among authors: cochran jr. Biochemistry. 2007 Aug 21;46(33):9453-61. doi: 10.1021/bi700652f. Epub 2007 Jul 27. Biochemistry. 2007. PMID: 17655329

9

Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.

Kimura RH, Jones DS, Jiang L, Miao Z, Cheng Z, Cochran JR. Kimura RH, et al. Among authors: cochran jr. PLoS One. 2011 Feb 18;6(2):e16112. doi: 10.1371/journal.pone.0016112. PLoS One. 2011. PMID: 21364742 Free PMC article.

10

Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging.

Moore SJ, Leung CL, Norton HK, Cochran JR. Moore SJ, et al. Among authors: cochran jr. PLoS One. 2013;8(4):e60498. doi: 10.1371/journal.pone.0060498. Epub 2013 Apr 3. PLoS One. 2013. PMID: 23573262 Free PMC article.

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