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Deubiquitylating enzymes and drug discovery: emerging opportunities.
Harrigan JA, Jacq X, Martin NM, Jackson SP. Harrigan JA, et al. Among authors: jackson sp. Nat Rev Drug Discov. 2018 Jan;17(1):57-78. doi: 10.1038/nrd.2017.152. Epub 2017 Sep 29. Nat Rev Drug Discov. 2018. PMID: 28959952 Free PMC article. Review.
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: jackson sp. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
Replication stress induces 53BP1-containing OPT domains in G1 cells.
Harrigan JA, Belotserkovskaya R, Coates J, Dimitrova DS, Polo SE, Bradshaw CR, Fraser P, Jackson SP. Harrigan JA, et al. Among authors: jackson sp. J Cell Biol. 2011 Apr 4;193(1):97-108. doi: 10.1083/jcb.201011083. Epub 2011 Mar 28. J Cell Biol. 2011. PMID: 21444690 Free PMC article.
Deubiquitylating enzymes and DNA damage response pathways.
Jacq X, Kemp M, Martin NM, Jackson SP. Jacq X, et al. Among authors: jackson sp. Cell Biochem Biophys. 2013 Sep;67(1):25-43. doi: 10.1007/s12013-013-9635-3. Cell Biochem Biophys. 2013. PMID: 23712866 Free PMC article. Review.
493 results