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Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
Williams SA, Murthy AC, DeLisle RK, Hyde C, Malarstig A, Ostroff R, Weiss SJ, Segal MR, Ganz P. Williams SA, et al. Among authors: murthy ac. Circulation. 2018 Mar 6;137(10):999-1010. doi: 10.1161/CIRCULATIONAHA.117.028213. Epub 2017 Oct 3. Circulation. 2018. PMID: 28974520 Free PMC article. Clinical Trial.
Proteomic cardiovascular risk assessment in chronic kidney disease.
Deo R, Dubin RF, Ren Y, Murthy AC, Wang J, Zheng H, Zheng Z, Feldman H, Shou H, Coresh J, Grams M, Surapaneni AL, Bhat Z, Cohen JB, Rahman M, He J, Saraf SL, Go AS, Kimmel PL, Vasan RS, Segal MR, Li H, Ganz P. Deo R, et al. Among authors: murthy ac. Eur Heart J. 2023 Jun 20;44(23):2095-2110. doi: 10.1093/eurheartj/ehad115. Eur Heart J. 2023. PMID: 37014015 Free PMC article.
Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes.
O'Connell LC, Johnson V, Hutton AK, Otis JP, Murthy AC, Liang MC, Wang SH, Fawzi NL, Mowry KL. O'Connell LC, et al. Among authors: murthy ac. bioRxiv [Preprint]. 2023 Nov 10:2023.11.10.566489. doi: 10.1101/2023.11.10.566489. bioRxiv. 2023. Update in: Sci Rep. 2024 Nov 13;14(1):27890. doi: 10.1038/s41598-024-79409-9 PMID: 37986933 Free PMC article. Updated. Preprint.
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.
Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, Gleixner AM, Diaz Z, Carey JL, Smirnov A, Padilla G, Lavorando E, Espy C, Shang Y, Huang EJ, Chesi A, Fawzi NL, Myong S, Donnelly CJ, Shorter J. Guo L, et al. Among authors: murthy ac. bioRxiv [Preprint]. 2023 Sep 4:2023.09.04.555754. doi: 10.1101/2023.09.04.555754. bioRxiv. 2023. PMID: 37732211 Free PMC article. Preprint.
23 results