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Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients.
Downes K, Marcovecchio ML, Clarke P, Cooper JD, Ferreira RC, Howson JM, Jolley J, Nutland S, Stevens HE, Walker NM, Wallace C, Dunger DB, Todd JA. Downes K, et al. Among authors: walker nm. Diabetologia. 2014 Feb;57(2):366-72. doi: 10.1007/s00125-013-3113-8. Epub 2013 Nov 22. Diabetologia. 2014. PMID: 24264051 Free PMC article.
IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.
Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML. Ferreira RC, et al. Among authors: walker nm. Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6. Diabetologia. 2015. PMID: 25652388 Free PMC article.
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, Rainbow DB, Hunter KM, Smith AN, Di Genova G, Herr MH, Dahlman I, Payne F, Smyth D, Lowe C, Twells RC, Howlett S, Healy B, Nutland S, Rance HE, Everett V, Smink LJ, Lam AC, Cordell HJ, Walker NM, Bordin C, Hulme J, Motzo C, Cucca F, Hess JF, Metzker ML, Rogers J, Gregory S, Allahabadia A, Nithiyananthan R, Tuomilehto-Wolf E, Tuomilehto J, Bingley P, Gillespie KM, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîrgovişte C, Savage DA, Maxwell AP, Carson DJ, Patterson CC, Franklyn JA, Clayton DG, Peterson LB, Wicker LS, Todd JA, Gough SC. Ueda H, et al. Among authors: walker nm. Nature. 2003 May 29;423(6939):506-11. doi: 10.1038/nature01621. Epub 2003 Apr 30. Nature. 2003. PMID: 12724780
Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.
Nejentsev S, Cooper JD, Godfrey L, Howson JM, Rance H, Nutland S, Walker NM, Guja C, Ionescu-Tirgovişte C, Savage DA, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Gillespie KM, Ring SM, Strachan DP, Widmer B, Dunger D, Todd JA. Nejentsev S, et al. Among authors: walker nm. Diabetes. 2004 Oct;53(10):2709-12. doi: 10.2337/diabetes.53.10.2709. Diabetes. 2004. PMID: 15448105
No evidence for association of the TATA-box binding protein glutamine repeat sequence or the flanking chromosome 6q27 region with type 1 diabetes.
Payne F, Smyth DJ, Pask R, Cooper JD, Masters J, Wang WY, Godfrey LM, Bowden G, Szeszko J, Smink LJ, Lam AC, Burren O, Walker NM, Nutland S, Rance H, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîrgovişte C, Todd JA, Twells RC. Payne F, et al. Among authors: walker nm. Biochem Biophys Res Commun. 2005 Jun 3;331(2):435-41. doi: 10.1016/j.bbrc.2005.03.203. Biochem Biophys Res Commun. 2005. PMID: 15850778
167 results