Chen X - Search Results

1

Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss.

Chowdhury S, Owens KN, Herr RJ, Jiang Q, Chen X, Johnson G, Groppi VE, Raible DW, Rubel EW, Simon JA. Chowdhury S, et al. Among authors: chen x. J Med Chem. 2018 Jan 11;61(1):84-97. doi: 10.1021/acs.jmedchem.7b00932. Epub 2017 Oct 27. J Med Chem. 2018. PMID: 28992413 Free PMC article.

2

Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators.

Rynearson KD, Buckle RN, Herr RJ, Mayhew NJ, Chen X, Paquette WD, Sakwa SA, Yang J, Barnes KD, Nguyen P, Mobley WC, Johnson G, Lin JH, Tanzi RE, Wagner SL. Rynearson KD, et al. Among authors: chen x. Bioorg Med Chem. 2020 Nov 15;28(22):115734. doi: 10.1016/j.bmc.2020.115734. Epub 2020 Sep 1. Bioorg Med Chem. 2020. PMID: 33007551 Free PMC article.

3

Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.

Chen X, Kern ER, Drach JC, Gullen E, Cheng YC, Zemlicka J. Chen X, et al. J Med Chem. 2003 Apr 10;46(8):1531-7. doi: 10.1021/jm0205245. J Med Chem. 2003. PMID: 12672254

4

Synthesis, antiviral, and antitumor activity of 2-substituted purine methylenecyclopropane analogues of nucleosides.

Qin X, Chen X, Wang K, Polin L, Kern ER, Drach JC, Gullen E, Cheng YC, Zemlicka J. Qin X, et al. Among authors: chen x. Bioorg Med Chem. 2006 Feb 15;14(4):1247-54. doi: 10.1016/j.bmc.2005.09.052. Epub 2005 Oct 18. Bioorg Med Chem. 2006. PMID: 16242337

5

Synthesis and SAR of vinca alkaloid analogues.

Voss ME, Ralph JM, Xie D, Manning DD, Chen X, Frank AJ, Leyhane AJ, Liu L, Stevens JM, Budde C, Surman MD, Friedrich T, Peace D, Scott IL, Wolf M, Johnson R. Voss ME, et al. Among authors: chen x. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1245-9. doi: 10.1016/j.bmcl.2008.12.077. Epub 2008 Dec 25. Bioorg Med Chem Lett. 2009. PMID: 19147348

6

Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides.

Chen X, Zemlicka J. Chen X, et al. J Org Chem. 2002 Jan 11;67(1):286-9. doi: 10.1021/jo010511j. J Org Chem. 2002. PMID: 11777473

7

Novel substrates for nitric oxide synthases.

Xian M, Fujiwara N, Wen Z, Cai T, Kazuma S, Janczuk AJ, Tang X, Telyatnikov VV, Zhang Y, Chen X, Miyamoto Y, Taniguchi N, Wang PG. Xian M, et al. Among authors: chen x. Bioorg Med Chem. 2002 Sep;10(9):3049-55. doi: 10.1016/s0968-0896(02)00155-4. Bioorg Med Chem. 2002. PMID: 12110328

8

Synthesis of (Z)-(2,3-bis-hydroxymethyl)methylenecyclopropane analogues of purine nucleosides.

Chen X, Matsumi S, Mitsuya H, Zemlickal J. Chen X, et al. Nucleosides Nucleotides Nucleic Acids. 2003 Mar;22(3):265-74. doi: 10.1081/NCN-120021426. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 12816385

9

NIR-II Imaging for Tracking the Spatiotemporal Immune Microenvironment in Atherosclerotic Plaques.

Shen L, Chen M, Su Y, Bi Y, Shu G, Chen W, Lu C, Zhao Z, Lv L, Zou J, Chen X, Ji J. Shen L, et al. Among authors: chen x. ACS Nano. 2024 Dec 4. doi: 10.1021/acsnano.4c10739. Online ahead of print. ACS Nano. 2024. PMID: 39630481

10

Characteristic volatile compounds of white tea with different storage times using E-nose, HS-GC-IMS, and HS-SPME-GC-MS.

Huang H, Chen X, Wang Y, Cheng Y, Liu Z, Hu Y, Wu X, Wu C, Xiong Z. Huang H, et al. Among authors: chen x. J Food Sci. 2024 Dec 4. doi: 10.1111/1750-3841.17535. Online ahead of print. J Food Sci. 2024. PMID: 39630468

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