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Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.
Pera M, Larrea D, Guardia-Laguarta C, Montesinos J, Velasco KR, Agrawal RR, Xu Y, Chan RB, Di Paolo G, Mehler MF, Perumal GS, Macaluso FP, Freyberg ZZ, Acin-Perez R, Enriquez JA, Schon EA, Area-Gomez E. Pera M, et al. EMBO J. 2017 Nov 15;36(22):3356-3371. doi: 10.15252/embj.201796797. Epub 2017 Oct 10. EMBO J. 2017. PMID: 29018038 Free PMC article.
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease.
Area-Gomez E, Del Carmen Lara Castillo M, Tambini MD, Guardia-Laguarta C, de Groof AJ, Madra M, Ikenouchi J, Umeda M, Bird TD, Sturley SL, Schon EA. Area-Gomez E, et al. EMBO J. 2012 Nov 5;31(21):4106-23. doi: 10.1038/emboj.2012.202. Epub 2012 Aug 14. EMBO J. 2012. PMID: 22892566 Free PMC article.
α-Synuclein is localized to mitochondria-associated ER membranes.
Guardia-Laguarta C, Area-Gomez E, Rüb C, Liu Y, Magrané J, Becker D, Voos W, Schon EA, Przedborski S. Guardia-Laguarta C, et al. J Neurosci. 2014 Jan 1;34(1):249-59. doi: 10.1523/JNEUROSCI.2507-13.2014. J Neurosci. 2014. PMID: 24381286 Free PMC article.
Mitochondrial genetics and disease.
Area-Gomez E, Schon EA. Area-Gomez E, et al. J Child Neurol. 2014 Sep;29(9):1208-15. doi: 10.1177/0883073814539561. Epub 2014 Jul 14. J Child Neurol. 2014. PMID: 25028417 Review.
60 results