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NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.
Ju J, Chen A, Deng Y, Liu M, Wang Y, Wang Y, Nie M, Wang C, Ding H, Yao B, Gui T, Li X, Xu Z, Ma C, Song Y, Kvansakul M, Zen K, Zhang CY, Luo C, Fang M, Huang DCS, Allis CD, Tan R, Zeng CK, Wei J, Zhao Q. Ju J, et al. Among authors: huang dcs. Nat Commun. 2017 Oct 13;8(1):928. doi: 10.1038/s41467-017-00988-5. Nat Commun. 2017. PMID: 29030587 Free PMC article.
CARM1-mediated methylation of protein arginine methyltransferase 5 represses human γ-globin gene expression in erythroleukemia cells.
Nie M, Wang Y, Guo C, Li X, Wang Y, Deng Y, Yao B, Gui T, Ma C, Liu M, Wang P, Wang R, Tan R, Fang M, Chen B, He Y, Huang DCS, Ju J, Zhao Q. Nie M, et al. Among authors: huang dcs. J Biol Chem. 2018 Nov 9;293(45):17454-17463. doi: 10.1074/jbc.RA118.004028. Epub 2018 Sep 26. J Biol Chem. 2018. PMID: 30257864 Free PMC article.
Transcriptional silencing of fetal hemoglobin expression by NonO.
Li X, Chen M, Liu B, Lu P, Lv X, Zhao X, Cui S, Xu P, Nakamura Y, Kurita R, Chen B, Huang DCS, Liu DP, Liu M, Zhao Q. Li X, et al. Among authors: huang dcs. Nucleic Acids Res. 2021 Sep 27;49(17):9711-9723. doi: 10.1093/nar/gkab671. Nucleic Acids Res. 2021. PMID: 34379783 Free PMC article.
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL. Chan TY, et al. Among authors: huang dcs. Nat Commun. 2021 Sep 9;12(1):5337. doi: 10.1038/s41467-021-25622-3. Nat Commun. 2021. PMID: 34504101 Free PMC article.
209 results