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Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity.
Uliassi E, Fiorani G, Krauth-Siegel RL, Bergamini C, Fato R, Bianchini G, Carlos Menéndez J, Molina MT, López-Montero E, Falchi F, Cavalli A, Gul S, Kuzikov M, Ellinger B, Witt G, Moraes CB, Freitas-Junior LH, Borsari C, Costi MP, Bolognesi ML. Uliassi E, et al. Among authors: bianchini g. Eur J Med Chem. 2017 Dec 1;141:138-148. doi: 10.1016/j.ejmech.2017.10.005. Epub 2017 Oct 3. Eur J Med Chem. 2017. PMID: 29031061
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. De Petrocellis L, et al. Among authors: bianchini g. J Med Chem. 2016 Jun 23;59(12):5661-83. doi: 10.1021/acs.jmedchem.5b01448. Epub 2016 Jun 14. J Med Chem. 2016. PMID: 27232526
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models.
Staderini M, Vanni S, Baldeschi AC, Giachin G, Zattoni M, Celauro L, Ferracin C, Bistaffa E, Moda F, Pérez DI, Martínez A, Martín MA, Martín-Cámara O, Cores Á, Bianchini G, Kammerer R, Menéndez JC, Legname G, Bolognesi ML. Staderini M, et al. Among authors: bianchini g. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114923. doi: 10.1016/j.ejmech.2022.114923. Epub 2022 Nov 15. Eur J Med Chem. 2023. PMID: 36423450 Free article.
B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.
González-Ruiz V, Pascua I, Fernández-Marcelo T, Ribelles P, Bianchini G, Sridharan V, Iniesta P, Ramos MT, Olives AI, Martín MA, Menéndez JC. González-Ruiz V, et al. Among authors: bianchini g. PLoS One. 2014 May 15;9(5):e95998. doi: 10.1371/journal.pone.0095998. eCollection 2014. PLoS One. 2014. PMID: 24830682 Free PMC article.
Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. De Petrocellis L, et al. Among authors: bianchini g. J Med Chem. 2016 Aug 25;59(16):7697. doi: 10.1021/acs.jmedchem.6b01091. Epub 2016 Aug 3. J Med Chem. 2016. PMID: 27487560 No abstract available.
Estrogen Signaling in Early-Stage Breast Cancer: Impact on Neoadjuvant Chemotherapy and Immunotherapy.
Corti C, Binboğa Kurt B, Koca B, Rahman T, Conforti F, Pala L, Bianchini G, Criscitiello C, Curigliano G, Garrido-Castro AC, Kabraji SK, Waks AG, Mittendorf EA, Tolaney SM. Corti C, et al. Among authors: bianchini g. Cancer Treat Rev. 2024 Nov 13;132:102852. doi: 10.1016/j.ctrv.2024.102852. Online ahead of print. Cancer Treat Rev. 2024. PMID: 39571402 Free article. Review.
Inhibition of phototrophic iron oxidation by nitric oxide in ferruginous environments.
Nikeleit V, Mellage A, Bianchini G, Sauter L, Buessecker S, Gotterbarm S, Schad M, Konhauser K, Zerkle AL, Sánchez-Baracaldo P, Kappler A, Bryce C. Nikeleit V, et al. Among authors: bianchini g. Nat Geosci. 2024;17(11):1169-1174. doi: 10.1038/s41561-024-01560-9. Epub 2024 Oct 4. Nat Geosci. 2024. PMID: 39526045 Free PMC article.
Development and validation of a gene expression-based Breast Cancer Purity Score.
Barreca M, Dugo M, Galbardi B, Győrffy B; NA-PHER2 consortium; NeoTRIP consortium; Valagussa P, Besozzi D, Viale G, Bianchini G, Gianni L, Callari M. Barreca M, et al. Among authors: bianchini g. NPJ Precis Oncol. 2024 Oct 24;8(1):242. doi: 10.1038/s41698-024-00730-7. NPJ Precis Oncol. 2024. PMID: 39448787 Free PMC article.
290 results