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Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity.
Uliassi E, Fiorani G, Krauth-Siegel RL, Bergamini C, Fato R, Bianchini G, Carlos Menéndez J, Molina MT, López-Montero E, Falchi F, Cavalli A, Gul S, Kuzikov M, Ellinger B, Witt G, Moraes CB, Freitas-Junior LH, Borsari C, Costi MP, Bolognesi ML. Uliassi E, et al. Among authors: molina mt. Eur J Med Chem. 2017 Dec 1;141:138-148. doi: 10.1016/j.ejmech.2017.10.005. Epub 2017 Oct 3. Eur J Med Chem. 2017. PMID: 29031061
Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni.
Ribeiro KA, de Carvalho CM, Molina MT, Lima EP, López-Montero E, Reys JR, de Oliveira MB, Pinto AV, Santana AE, Goulart MO. Ribeiro KA, et al. Among authors: molina mt. Acta Trop. 2009 Jul;111(1):44-50. doi: 10.1016/j.actatropica.2009.02.008. Epub 2009 Mar 6. Acta Trop. 2009. PMID: 19426662 Free article.
New Imidazole-Based Compounds Active Against Trypanosoma cruzi.
Adeyemi OS, Molina MT, Eseola AO, Fonseca-Berzal C, Gómez-Barrio A. Adeyemi OS, et al. Among authors: molina mt. Comb Chem High Throughput Screen. 2017;20(1):20-24. doi: 10.2174/1386207320666170110141907. Comb Chem High Throughput Screen. 2017. PMID: 28071587
Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative.
Montenegro RC, Araújo AJ, Molina MT, Marinho Filho JD, Rocha DD, Lopéz-Montero E, Goulart MO, Bento ES, Alves AP, Pessoa C, de Moraes MO, Costa-Lotufo LV. Montenegro RC, et al. Among authors: molina mt. Chem Biol Interact. 2010 Mar 30;184(3):439-48. doi: 10.1016/j.cbi.2010.01.041. Epub 2010 Feb 4. Chem Biol Interact. 2010. PMID: 20138029 Free article.
In vitro antiamyloidogenic properties of 1,4-naphthoquinones.
Bermejo-Bescós P, Martín-Aragón S, Jiménez-Aliaga KL, Ortega A, Molina MT, Buxaderas E, Orellana G, Csákÿ AG. Bermejo-Bescós P, et al. Among authors: molina mt. Biochem Biophys Res Commun. 2010 Sep 10;400(1):169-74. doi: 10.1016/j.bbrc.2010.08.038. Epub 2010 Aug 13. Biochem Biophys Res Commun. 2010. PMID: 20709023
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