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Page 1
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: ostrowski mc. Oncogene. 2017 Nov 23;36(47):6658. doi: 10.1038/onc.2017.347. Epub 2017 Oct 16. Oncogene. 2017. PMID: 29035387
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G. Trimboli AJ, et al. Among authors: ostrowski mc. Nature. 2009 Oct 22;461(7267):1084-91. doi: 10.1038/nature08486. Nature. 2009. PMID: 19847259 Free PMC article.
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC. Bronisz A, et al. Among authors: ostrowski mc. Nat Cell Biol. 2011 Dec 18;14(2):159-67. doi: 10.1038/ncb2396. Nat Cell Biol. 2011. PMID: 22179046 Free PMC article.
Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC. Wallace JA, et al. Among authors: ostrowski mc. PLoS One. 2013 Aug 16;8(8):e71533. doi: 10.1371/journal.pone.0071533. eCollection 2013. PLoS One. 2013. PMID: 23977064 Free PMC article.
Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis.
Wallace JA, Pitarresi JR, Sharma N, Palettas M, Cuitiño MC, Sizemore ST, Yu L, Sanderlin A, Rosol TJ, Mehta KD, Sizemore GM, Ostrowski MC. Wallace JA, et al. Among authors: ostrowski mc. Front Oncol. 2014 Apr 23;4:87. doi: 10.3389/fonc.2014.00087. eCollection 2014. Front Oncol. 2014. PMID: 24795864 Free PMC article.
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC. Mathsyaraja H, et al. Among authors: ostrowski mc. Oncogene. 2015 Jul;34(28):3651-61. doi: 10.1038/onc.2014.294. Epub 2014 Sep 22. Oncogene. 2015. PMID: 25241894 Free PMC article.
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Caserta E, et al. Among authors: ostrowski mc. Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115. Genes Dev. 2015. PMID: 26302789 Free PMC article.
E2f3 in tumor macrophages promotes lung metastasis.
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Ostrowski MC, Leone G. Trikha P, et al. Among authors: ostrowski mc. Oncogene. 2016 Jul 14;35(28):3636-46. doi: 10.1038/onc.2015.429. Epub 2015 Nov 9. Oncogene. 2016. PMID: 26549026 Free PMC article.
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC. Liu X, et al. Among authors: ostrowski mc. Genes Dev. 2016 Sep 1;30(17):1943-55. doi: 10.1101/gad.283499.116. Epub 2016 Sep 15. Genes Dev. 2016. PMID: 27633013 Free PMC article.
182 results