Popovic R - Search Results

1

UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.

Ezponda T, Dupéré-Richer D, Will CM, Small EC, Varghese N, Patel T, Nabet B, Popovic R, Oyer J, Bulic M, Zheng Y, Huang X, Shah MY, Maji S, Riva A, Occhionorelli M, Tonon G, Kelleher N, Keats J, Licht JD. Ezponda T, et al. Among authors: popovic r. Cell Rep. 2017 Oct 17;21(3):628-640. doi: 10.1016/j.celrep.2017.09.078. Cell Rep. 2017. PMID: 29045832 Free PMC article.

2

Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape.

Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, Licht JD. Nabet B, et al. Among authors: popovic r. Cell Rep. 2015 Aug 25;12(8):1300-13. doi: 10.1016/j.celrep.2015.06.078. Epub 2015 Aug 13. Cell Rep. 2015. PMID: 26279576 Free PMC article.

3

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer.

Ezponda T, Popovic R, Shah MY, Martinez-Garcia E, Zheng Y, Min DJ, Will C, Neri A, Kelleher NL, Yu J, Licht JD. Ezponda T, et al. Among authors: popovic r. Oncogene. 2013 Jun 6;32(23):2882-90. doi: 10.1038/onc.2012.297. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797064 Free PMC article.

4

MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.

Min DJ, Ezponda T, Kim MK, Will CM, Martinez-Garcia E, Popovic R, Basrur V, Elenitoba-Johnson KS, Licht JD. Min DJ, et al. Among authors: popovic r. Leukemia. 2013 Mar;27(3):686-94. doi: 10.1038/leu.2012.269. Epub 2012 Sep 13. Leukemia. 2013. PMID: 22972034 Free PMC article.

5

MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.

Shah MY, Martinez-Garcia E, Phillip JM, Chambliss AB, Popovic R, Ezponda T, Small EC, Will C, Phillip MP, Neri P, Bahlis NJ, Wirtz D, Licht JD. Shah MY, et al. Among authors: popovic r. Oncogene. 2016 Nov 10;35(45):5905-5915. doi: 10.1038/onc.2016.116. Epub 2016 Apr 25. Oncogene. 2016. PMID: 27109101 Free PMC article.

6

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. Martinez-Garcia E, et al. Among authors: popovic r. Blood. 2011 Jan 6;117(1):211-20. doi: 10.1182/blood-2010-07-298349. Epub 2010 Oct 25. Blood. 2011. PMID: 20974671 Free PMC article.

7

MEK and MAF in myeloma therapy.

Popovic R, Licht JD. Popovic R, et al. Blood. 2011 Feb 24;117(8):2300-2. doi: 10.1182/blood-2011-01-327262. Blood. 2011. PMID: 21350059 Free article.

8

Emerging epigenetic targets and therapies in cancer medicine.

Popovic R, Licht JD. Popovic R, et al. Cancer Discov. 2012 May;2(5):405-13. doi: 10.1158/2159-8290.CD-12-0076. Epub 2012 Apr 23. Cancer Discov. 2012. PMID: 22588878 Free PMC article. Review.

9

Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3.

Zheng Y, Sweet SM, Popovic R, Martinez-Garcia E, Tipton JD, Thomas PM, Licht JD, Kelleher NL. Zheng Y, et al. Among authors: popovic r. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13549-54. doi: 10.1073/pnas.1205707109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869745 Free PMC article.

10

Epigenetic therapy of hematological malignancies: where are we now?

Popovic R, Shah MY, Licht JD. Popovic R, et al. Ther Adv Hematol. 2013 Apr;4(2):81-91. doi: 10.1177/2040620712466864. Ther Adv Hematol. 2013. PMID: 23610616 Free PMC article.

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