Schön A - Search Results

1

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.

Herschhorn A, Gu C, Moraca F, Ma X, Farrell M, Smith AB 3rd, Pancera M, Kwong PD, Schön A, Freire E, Abrams C, Blanchard SC, Mothes W, Sodroski JG. Herschhorn A, et al. Among authors: schon a. Nat Commun. 2017 Oct 19;8(1):1049. doi: 10.1038/s41467-017-01119-w. Nat Commun. 2017. PMID: 29051495 Free PMC article.

2

Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1.

Schön A, Freire E. Schön A, et al. Biochemistry. 1989 Jun 13;28(12):5019-24. doi: 10.1021/bi00438a017. Biochemistry. 1989. PMID: 2765522

3

The binding of HIV-1 protease inhibitors to human serum proteins.

Schön A, del Mar Ingaramo M, Freire E. Schön A, et al. Biophys Chem. 2003 Sep;105(2-3):221-30. doi: 10.1016/s0301-4622(03)00071-1. Biophys Chem. 2003. PMID: 14499894

4

Multidrug resistance to HIV-1 protease inhibition requires cooperative coupling between distal mutations.

Ohtaka H, Schön A, Freire E. Ohtaka H, et al. Among authors: schon a. Biochemistry. 2003 Nov 25;42(46):13659-66. doi: 10.1021/bi0350405. Biochemistry. 2003. PMID: 14622012

5

Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.

Velazquez-Campoy A, Muzammil S, Ohtaka H, Schön A, Vega S, Freire E. Velazquez-Campoy A, et al. Among authors: schon a. Curr Drug Targets Infect Disord. 2003 Dec;3(4):311-28. doi: 10.2174/1568005033481051. Curr Drug Targets Infect Disord. 2003. PMID: 14754432 Review.

6

Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.

Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Leavitt SA, et al. Among authors: schon a. Curr Protein Pept Sci. 2004 Feb;5(1):1-8. doi: 10.2174/1389203043486955. Curr Protein Pept Sci. 2004. PMID: 14965316 Review.

7

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.

Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB 3rd, Sodroski JG. Si Z, et al. Among authors: schon a. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5036-41. doi: 10.1073/pnas.0307953101. Epub 2004 Mar 29. Proc Natl Acad Sci U S A. 2004. PMID: 15051887 Free PMC article.

8

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.

Ohtaka H, Muzammil S, Schön A, Velazquez-Campoy A, Vega S, Freire E. Ohtaka H, et al. Among authors: schon a. Int J Biochem Cell Biol. 2004 Sep;36(9):1787-99. doi: 10.1016/j.biocel.2004.02.021. Int J Biochem Cell Biol. 2004. PMID: 15183345 Review.

9

Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.

Pancera M, Lebowitz J, Schön A, Zhu P, Freire E, Kwong PD, Roux KH, Sodroski J, Wyatt R. Pancera M, et al. Among authors: schon a. J Virol. 2005 Aug;79(15):9954-69. doi: 10.1128/JVI.79.15.9954-9969.2005. J Virol. 2005. PMID: 16014956 Free PMC article.

10

Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins.

Aguilar RC, Longhi SA, Shaw JD, Yeh LY, Kim S, Schön A, Freire E, Hsu A, McCormick WK, Watson HA, Wendland B. Aguilar RC, et al. Among authors: schon a. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4116-21. doi: 10.1073/pnas.0510513103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537494 Free PMC article.

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