Self A - Search Results

1

Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.

Whittaker SR, Barlow C, Martin MP, Mancusi C, Wagner S, Self A, Barrie E, Te Poele R, Sharp S, Brown N, Wilson S, Jackson W, Fischer PM, Clarke PA, Walton MI, McDonald E, Blagg J, Noble M, Garrett MD, Workman P. Whittaker SR, et al. Among authors: self a. Mol Oncol. 2018 Mar;12(3):287-304. doi: 10.1002/1878-0261.12148. Epub 2018 Jan 28. Mol Oncol. 2018. PMID: 29063678 Free PMC article.

2

A Genome-scale CRISPR Screen Identifies the ERBB and mTOR Signaling Networks as Key Determinants of Response to PI3K Inhibition in Pancreatic Cancer.

Milton CK, Self AJ, Clarke PA, Banerji U, Piccioni F, Root DE, Whittaker SR. Milton CK, et al. Among authors: self aj. Mol Cancer Ther. 2020 Jul;19(7):1423-1435. doi: 10.1158/1535-7163.MCT-19-1131. Epub 2020 May 5. Mol Cancer Ther. 2020. PMID: 32371585 Free PMC article.

3

Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.

Wagner S, Vlachogiannis G, De Haven Brandon A, Valenti M, Box G, Jenkins L, Mancusi C, Self A, Manodoro F, Assiotis I, Robinson P, Chauhan R, Rust AG, Matthews N, Eason K, Khan K, Starling N, Cunningham D, Sadanandam A, Isacke CM, Kirkin V, Valeri N, Whittaker SR. Wagner S, et al. Among authors: self a. Oncogene. 2019 Mar;38(10):1717-1733. doi: 10.1038/s41388-018-0554-z. Epub 2018 Oct 23. Oncogene. 2019. PMID: 30353166 Free PMC article.

4

Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.

Wagner S, Vlachogiannis G, De Haven Brandon A, Valenti M, Box G, Jenkins L, Mancusi C, Self A, Manodoro F, Assiotis I, Robinson P, Chauhan R, Rust AG, Matthews N, Eason K, Khan K, Starling N, Cunningham D, Sadanandam A, Isacke CM, Kirkin V, Valeri N, Whittaker SR. Wagner S, et al. Among authors: self a. Oncogene. 2019 Jul;38(28):5746. doi: 10.1038/s41388-019-0835-1. Oncogene. 2019. PMID: 31147600 Free PMC article.

5

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

Paterson HF, Self AJ, Garrett MD, Just I, Aktories K, Hall A. Paterson HF, et al. Among authors: self aj. J Cell Biol. 1990 Sep;111(3):1001-7. doi: 10.1083/jcb.111.3.1001. J Cell Biol. 1990. PMID: 2118140 Free PMC article.

6

Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins.

Garrett MD, Self AJ, van Oers C, Hall A. Garrett MD, et al. Among authors: self aj. J Biol Chem. 1989 Jan 5;264(1):10-3. J Biol Chem. 1989. PMID: 2491843 Free article.

7

rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo.

Ridley AJ, Self AJ, Kasmi F, Paterson HF, Hall A, Marshall CJ, Ellis C. Ridley AJ, et al. Among authors: self aj. EMBO J. 1993 Dec 15;12(13):5151-60. doi: 10.1002/j.1460-2075.1993.tb06210.x. EMBO J. 1993. PMID: 8262058 Free PMC article.

8

Different structural organization of Ras and Rho effector domains.

Self AJ, Paterson HF, Hall A. Self AJ, et al. Oncogene. 1993 Mar;8(3):655-61. Oncogene. 1993. PMID: 8437849

9

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators.

Caron E, Self AJ, Hall A. Caron E, et al. Among authors: self aj. Curr Biol. 2000 Aug 24;10(16):974-8. doi: 10.1016/s0960-9822(00)00641-2. Curr Biol. 2000. PMID: 10985384 Free article.

10

Analysis of R-Ras signalling pathways.

Self AJ, Caron E, Paterson HF, Hall A. Self AJ, et al. J Cell Sci. 2001 Apr;114(Pt 7):1357-66. doi: 10.1242/jcs.114.7.1357. J Cell Sci. 2001. PMID: 11257001

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