Te Poele R - Search Results

1

Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.

Whittaker SR, Barlow C, Martin MP, Mancusi C, Wagner S, Self A, Barrie E, Te Poele R, Sharp S, Brown N, Wilson S, Jackson W, Fischer PM, Clarke PA, Walton MI, McDonald E, Blagg J, Noble M, Garrett MD, Workman P. Whittaker SR, et al. Among authors: te poele r. Mol Oncol. 2018 Mar;12(3):287-304. doi: 10.1002/1878-0261.12148. Epub 2018 Jan 28. Mol Oncol. 2018. PMID: 29063678 Free PMC article.

2

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.

Clarke PA, te Poele R, Wooster R, Workman P. Clarke PA, et al. Among authors: te poele r. Biochem Pharmacol. 2001 Nov 15;62(10):1311-36. doi: 10.1016/s0006-2952(01)00785-7. Biochem Pharmacol. 2001. PMID: 11709192 Review.

3

Gene expression microarray technologies in the development of new therapeutic agents.

Clarke PA, te Poele R, Workman P. Clarke PA, et al. Among authors: te poele r. Eur J Cancer. 2004 Nov;40(17):2560-91. doi: 10.1016/j.ejca.2004.07.024. Eur J Cancer. 2004. PMID: 15541959 Review.

4

Disruption of WT1 gene expression and exon 5 splicing following cytotoxic drug treatment: antisense down-regulation of exon 5 alters target gene expression and inhibits cell survival.

Renshaw J, Orr RM, Walton MI, Te Poele R, Williams RD, Wancewicz EV, Monia BP, Workman P, Pritchard-Jones K. Renshaw J, et al. Among authors: te poele r. Mol Cancer Ther. 2004 Nov;3(11):1467-84. Mol Cancer Ther. 2004. PMID: 15542786

5

Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways.

Knowles HJ, te Poele RH, Workman P, Harris AL. Knowles HJ, et al. Biochem Pharmacol. 2006 Feb 28;71(5):646-56. doi: 10.1016/j.bcp.2005.11.019. Epub 2006 Jan 18. Biochem Pharmacol. 2006. PMID: 16386710

6

AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines.

Hockley SL, Arlt VM, Brewer D, Te Poele R, Workman P, Giddings I, Phillips DH. Hockley SL, et al. Among authors: te poele r. Chem Res Toxicol. 2007 Dec;20(12):1797-810. doi: 10.1021/tx700252n. Epub 2007 Oct 19. Chem Res Toxicol. 2007. PMID: 17944540

7

The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis.

Whittaker SR, Te Poele RH, Chan F, Linardopoulos S, Walton MI, Garrett MD, Workman P. Whittaker SR, et al. Among authors: te poele rh. Cell Cycle. 2007 Dec 15;6(24):3114-31. doi: 10.4161/cc.6.24.5142. Epub 2007 Oct 5. Cell Cycle. 2007. PMID: 18075315

8

Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity.

Chan F, Sun C, Perumal M, Nguyen QD, Bavetsias V, McDonald E, Martins V, Wilsher NE, Raynaud FI, Valenti M, Eccles S, Te Poele R, Workman P, Aboagye EO, Linardopoulos S. Chan F, et al. Among authors: te poele r. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3147-57. doi: 10.1158/1535-7163.MCT-07-2156. Mol Cancer Ther. 2007. PMID: 18089709

9

Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma.

Guillard S, Clarke PA, Te Poele R, Mohri Z, Bjerke L, Valenti M, Raynaud F, Eccles SA, Workman P. Guillard S, et al. Among authors: te poele r. Cell Cycle. 2009 Feb 1;8(3):443-53. doi: 10.4161/cc.8.3.7643. Epub 2009 Feb 16. Cell Cycle. 2009. PMID: 19177002

10

Correlation of overall survival with gene expression profiles in a prospective study of resectable esophageal cancer.

Rao S, Welsh L, Cunningham D, te-Poele RH, Benson M, Norman A, Saffery C, Giddings I, Workman P, Clarke PA. Rao S, et al. Clin Colorectal Cancer. 2011 Mar 1;10(1):48-56. doi: 10.3816/CCC.2011.n.007. Clin Colorectal Cancer. 2011. PMID: 21609936

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