Jeffery LE - Search Results

1

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint.

Jeffery LE, Henley P, Marium N, Filer A, Sansom DM, Hewison M, Raza K. Jeffery LE, et al. J Autoimmun. 2018 Mar;88:50-60. doi: 10.1016/j.jaut.2017.10.001. Epub 2017 Oct 21. J Autoimmun. 2018. PMID: 29066221 Free PMC article.

2

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

Jeffery LE, Burke F, Mura M, Zheng Y, Qureshi OS, Hewison M, Walker LS, Lammas DA, Raza K, Sansom DM. Jeffery LE, et al. J Immunol. 2009 Nov 1;183(9):5458-67. doi: 10.4049/jimmunol.0803217. J Immunol. 2009. PMID: 19843932 Free PMC article.

3

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.

Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, Schmidt EM, Baker J, Jeffery LE, Kaur S, Briggs Z, Hou TZ, Futter CE, Anderson G, Walker LS, Sansom DM. Qureshi OS, et al. Among authors: jeffery le. Science. 2011 Apr 29;332(6029):600-3. doi: 10.1126/science.1202947. Epub 2011 Apr 7. Science. 2011. PMID: 21474713 Free PMC article.

4

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation.

Qureshi OS, Kaur S, Hou TZ, Jeffery LE, Poulter NS, Briggs Z, Kenefeck R, Willox AK, Royle SJ, Rappoport JZ, Sansom DM. Qureshi OS, et al. Among authors: jeffery le. J Biol Chem. 2012 Mar 16;287(12):9429-40. doi: 10.1074/jbc.M111.304329. Epub 2012 Jan 19. J Biol Chem. 2012. PMID: 22262842 Free PMC article.

5

Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses.

Jeffery LE, Wood AM, Qureshi OS, Hou TZ, Gardner D, Briggs Z, Kaur S, Raza K, Sansom DM. Jeffery LE, et al. J Immunol. 2012 Dec 1;189(11):5155-64. doi: 10.4049/jimmunol.1200786. Epub 2012 Oct 19. J Immunol. 2012. PMID: 23087405 Free PMC article.

6

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis.

Liaskou E, Jeffery LE, Trivedi PJ, Reynolds GM, Suresh S, Bruns T, Adams DH, Sansom DM, Hirschfield GM. Liaskou E, et al. Among authors: jeffery le. Gastroenterology. 2014 Jul;147(1):221-232.e7. doi: 10.1053/j.gastro.2014.04.003. Epub 2014 Apr 12. Gastroenterology. 2014. PMID: 24726754 Free PMC article.

7

Understanding the CD28/CTLA-4 (CD152) pathway and its implications for costimulatory blockade.

Gardner D, Jeffery LE, Sansom DM. Gardner D, et al. Among authors: jeffery le. Am J Transplant. 2014 Sep;14(9):1985-91. doi: 10.1111/ajt.12834. Epub 2014 Aug 6. Am J Transplant. 2014. PMID: 25098238 Free article. Review.

8

Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function.

Jeffery LE, Qureshi OS, Gardner D, Hou TZ, Briggs Z, Soskic B, Baker J, Raza K, Sansom DM. Jeffery LE, et al. PLoS One. 2015 Jul 2;10(7):e0131539. doi: 10.1371/journal.pone.0131539. eCollection 2015. PLoS One. 2015. PMID: 26134669 Free PMC article.

9

1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept.

Gardner DH, Jeffery LE, Soskic B, Briggs Z, Hou TZ, Raza K, Sansom DM. Gardner DH, et al. Among authors: jeffery le. J Immunol. 2015 Sep 15;195(6):2657-65. doi: 10.4049/jimmunol.1500306. Epub 2015 Aug 14. J Immunol. 2015. PMID: 26276872 Free PMC article.

10

Vitamin D in rheumatoid arthritis-towards clinical application.

Jeffery LE, Raza K, Hewison M. Jeffery LE, et al. Nat Rev Rheumatol. 2016 Apr;12(4):201-10. doi: 10.1038/nrrheum.2015.140. Epub 2015 Oct 13. Nat Rev Rheumatol. 2016. PMID: 26481434 Review.

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