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Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs.
Jayaram DR, Frost S, Argov C, Liju VB, Anto NP, Muraleedharan A, Ben-Ari A, Sinay R, Smoly I, Novoplansky O, Isakov N, Toiber D, Keasar C, Elkabets M, Yeger-Lotem E, Livneh E. Jayaram DR, et al. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2018899118. doi: 10.1073/pnas.2018899118. Epub 2021 Sep 30. Proc Natl Acad Sci U S A. 2021. PMID: 34593629 Free PMC article.
Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation.
Simonovsky E, Sharon M, Ziv M, Mauer O, Hekselman I, Jubran J, Vinogradov E, Argov CM, Basha O, Kerber L, Yogev Y, Segrè AV, Im HK; GTEx Consortium; Birk O, Rokach L, Yeger-Lotem E. Simonovsky E, et al. Among authors: argov cm. Mol Syst Biol. 2023 Aug 8;19(8):e11407. doi: 10.15252/msb.202211407. Epub 2023 May 26. Mol Syst Biol. 2023. PMID: 37232043 Free PMC article.
Tissue-aware interpretation of genetic variants advances the etiology of rare diseases.
Argov CM, Shneyour A, Jubran J, Sabag E, Mansbach A, Sepunaru Y, Filtzer E, Gruber G, Volozhinsky M, Yogev Y, Birk O, Chalifa-Caspi V, Rokach L, Yeger-Lotem E. Argov CM, et al. Mol Syst Biol. 2024 Nov;20(11):1187-1206. doi: 10.1038/s44320-024-00061-6. Epub 2024 Sep 16. Mol Syst Biol. 2024. PMID: 39285047 Free PMC article.