Hecht JR - Search Results

1

A Randomized, Double-Blind, Placebo-Controlled Phase II Study of the Efficacy and Safety of Monotherapy Ontuxizumab (MORAb-004) Plus Best Supportive Care in Patients with Chemorefractory Metastatic Colorectal Cancer.

Grothey A, Strosberg JR, Renfro LA, Hurwitz HI, Marshall JL, Safran H, Guarino MJ, Kim GP, Hecht JR, Weil SC, Heyburn J, Wang W, Schweizer C, O'Shannessy DJ, Diaz LA Jr. Grothey A, et al. Among authors: hecht jr. Clin Cancer Res. 2018 Jan 15;24(2):316-325. doi: 10.1158/1078-0432.CCR-17-1558. Epub 2017 Oct 30. Clin Cancer Res. 2018. PMID: 29084918 Clinical Trial.

2

Phase II trial of irinotecan in combination with amifostine in patients with advanced colorectal carcinoma.

Delioukina ML, Prager D, Parson M, Hecht JR, Rosen P, Rosen LS. Delioukina ML, et al. Among authors: hecht jr. Cancer. 2002 Apr 15;94(8):2174-9. doi: 10.1002/cncr.10432. Cancer. 2002. PMID: 12001114 Free article. Clinical Trial.

3

A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma.

Hecht JR, Bedford R, Abbruzzese JL, Lahoti S, Reid TR, Soetikno RM, Kirn DH, Freeman SM. Hecht JR, et al. Clin Cancer Res. 2003 Feb;9(2):555-61. Clin Cancer Res. 2003. PMID: 12576418 Clinical Trial.

4

Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer.

Fuchs CS, Moore MR, Harker G, Villa L, Rinaldi D, Hecht JR. Fuchs CS, et al. Among authors: hecht jr. J Clin Oncol. 2003 Mar 1;21(5):807-14. doi: 10.1200/JCO.2003.08.058. J Clin Oncol. 2003. PMID: 12610178 Clinical Trial.

5

Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial.

Kabbinavar FF, Schulz J, McCleod M, Patel T, Hamm JT, Hecht JR, Mass R, Perrou B, Nelson B, Novotny WF. Kabbinavar FF, et al. Among authors: hecht jr. J Clin Oncol. 2005 Jun 1;23(16):3697-705. doi: 10.1200/JCO.2005.05.112. Epub 2005 Feb 28. J Clin Oncol. 2005. PMID: 15738537 Clinical Trial.

6

A phase III randomized, open-label, controlled trial of chemotherapy and bevacizumab with or without panitumumab in the first-line treatment of patients with metastatic colorectal cancer.

Wainberg Z, Hecht JR. Wainberg Z, et al. Among authors: hecht jr. Clin Colorectal Cancer. 2006 Jan;5(5):363-7. doi: 10.3816/CCC.2006.n.008. Clin Colorectal Cancer. 2006. PMID: 16512997 No abstract available.

7

Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer.

Hecht JR, Patnaik A, Berlin J, Venook A, Malik I, Tchekmedyian S, Navale L, Amado RG, Meropol NJ. Hecht JR, et al. Cancer. 2007 Sep 1;110(5):980-8. doi: 10.1002/cncr.22915. Cancer. 2007. PMID: 17671985 Free article. Clinical Trial.

8

A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer.

Hecht JR, Mitchell E, Chidiac T, Scroggin C, Hagenstad C, Spigel D, Marshall J, Cohn A, McCollum D, Stella P, Deeter R, Shahin S, Amado RG. Hecht JR, et al. J Clin Oncol. 2009 Feb 10;27(5):672-80. doi: 10.1200/JCO.2008.19.8135. Epub 2008 Dec 29. J Clin Oncol. 2009. PMID: 19114685 Clinical Trial.

9

Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.

Wainberg ZA, Anghel A, Desai AJ, Ayala R, Luo T, Safran B, Fejzo MS, Hecht JR, Slamon DJ, Finn RS. Wainberg ZA, et al. Among authors: hecht jr. Clin Cancer Res. 2010 Mar 1;16(5):1509-19. doi: 10.1158/1078-0432.CCR-09-1112. Epub 2010 Feb 23. Clin Cancer Res. 2010. PMID: 20179222

10

Lack of correlation between epidermal growth factor receptor status and response to Panitumumab monotherapy in metastatic colorectal cancer.

Hecht JR, Mitchell E, Neubauer MA, Burris HA 3rd, Swanson P, Lopez T, Buchanan G, Reiner M, Gansert J, Berlin J. Hecht JR, et al. Clin Cancer Res. 2010 Apr 1;16(7):2205-13. doi: 10.1158/1078-0432.CCR-09-2017. Epub 2010 Mar 23. Clin Cancer Res. 2010. PMID: 20332321 Clinical Trial.

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