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Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, Nwulia E, Henning U, Ferrea S, Luckhaus C, Ekelund J, Veijola J, Järvelin MR, Hennah W, Korth C. Bader V, et al. Among authors: trossbach sv. Hum Mol Genet. 2012 Oct 15;21(20):4406-18. doi: 10.1093/hmg/dds273. Epub 2012 Jul 13. Hum Mol Genet. 2012. PMID: 22798627 Free PMC article.
Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1.
Ramos A, Rodríguez-Seoane C, Rosa I, Trossbach SV, Ortega-Alonso A, Tomppo L, Ekelund J, Veijola J, Järvelin MR, Alonso J, Veiga S, Sawa A, Hennah W, García A, Korth C, Requena JR. Ramos A, et al. Among authors: trossbach sv. Hum Mol Genet. 2014 Nov 15;23(22):5859-65. doi: 10.1093/hmg/ddu303. Epub 2014 Jun 16. Hum Mol Genet. 2014. PMID: 24934694 Free PMC article.
Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.
Trossbach SV, Bader V, Hecher L, Pum ME, Masoud ST, Prikulis I, Schäble S, de Souza Silva MA, Su P, Boulat B, Chwiesko C, Poschmann G, Stühler K, Lohr KM, Stout KA, Oskamp A, Godsave SF, Müller-Schiffmann A, Bilzer T, Steiner H, Peters PJ, Bauer A, Sauvage M, Ramsey AJ, Miller GW, Liu F, Seeman P, Brandon NJ, Huston JP, Korth C. Trossbach SV, et al. Mol Psychiatry. 2016 Nov;21(11):1561-1572. doi: 10.1038/mp.2015.194. Epub 2016 Jan 12. Mol Psychiatry. 2016. PMID: 26754951 Free PMC article.
26 results