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Page 1
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia.
Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Fröhling S, Balachandran S, Skorski T, Garcia BA, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM. Di Marcantonio D, et al. Among authors: milsom md. Clin Cancer Res. 2018 Feb 1;24(3):608-618. doi: 10.1158/1078-0432.CCR-17-2684. Epub 2017 Nov 10. Clin Cancer Res. 2018. PMID: 29127121 Free PMC article.
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.
Placke T, Faber K, Nonami A, Putwain SL, Salih HR, Heidel FH, Krämer A, Root DE, Barbie DA, Krivtsov AV, Armstrong SA, Hahn WC, Huntly BJ, Sykes SM, Milsom MD, Scholl C, Fröhling S. Placke T, et al. Among authors: milsom md. Blood. 2014 Jul 3;124(1):13-23. doi: 10.1182/blood-2014-02-558114. Epub 2014 Apr 24. Blood. 2014. PMID: 24764564 Free PMC article.
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.
Rudat S, Pfaus A, Cheng YY, Holtmann J, Ellegast JM, Bühler C, Marcantonio DD, Martinez E, Göllner S, Wickenhauser C, Müller-Tidow C, Lutz C, Bullinger L, Milsom MD, Sykes SM, Fröhling S, Scholl C. Rudat S, et al. Among authors: milsom md. Leukemia. 2018 Oct;32(10):2189-2202. doi: 10.1038/s41375-018-0102-4. Epub 2018 Mar 22. Leukemia. 2018. PMID: 29654265
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Scheller M, Ludwig AK, Göllner S, Rohde C, Krämer S, Stäble S, Janssen M, Müller JA, He L, Bäumer N, Arnold C, Gerß J, Schönung M, Thiede C, Niederwieser C, Niederwieser D, Serve H, Berdel WE, Thiem U, Hemmerling I, Leuschner F, Plass C, Schlesner M, Zaugg J, Milsom MD, Trumpp A, Pabst C, Lipka DB, Müller-Tidow C. Scheller M, et al. Among authors: milsom md. Nat Cancer. 2021 May;2(5):527-544. doi: 10.1038/s43018-021-00213-9. Epub 2021 May 25. Nat Cancer. 2021. PMID: 35122024
Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis.
Schönung M, Hartmann M, Krämer S, Stäble S, Hakobyan M, Kleinert E, Aurich T, Cobanoglu D, Heidel FH, Fröhling S, Milsom MD, Schlesner M, Lutsik P, Lipka DB. Schönung M, et al. Among authors: milsom md. Exp Hematol. 2023 Jan;117:24-42.e7. doi: 10.1016/j.exphem.2022.11.001. Epub 2022 Nov 8. Exp Hematol. 2023. PMID: 36368558 Free article.
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2.
Pastoors D, Havermans M, Mulet-Lazaro R, Brian D, Noort W, Grasel J, Hoogenboezem R, Smeenk L, Demmers JAA, Milsom MD, Enver T, Groen RWJ, Bindels E, Delwel R. Pastoors D, et al. Among authors: milsom md. Sci Adv. 2024 May 17;10(20):eadk9076. doi: 10.1126/sciadv.adk9076. Epub 2024 May 15. Sci Adv. 2024. PMID: 38748792 Free PMC article.
Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
Milsom MD, Jerabek-Willemsen M, Harris CE, Schambach A, Broun E, Bailey J, Jansen M, Schleimer D, Nattamai K, Wilhelm J, Watson A, Geiger H, Margison GP, Moritz T, Baum C, Thomale J, Williams DA. Milsom MD, et al. Cancer Res. 2008 Aug 1;68(15):6171-80. doi: 10.1158/0008-5472.CAN-08-0320. Cancer Res. 2008. PMID: 18676840 Free PMC article.
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Sonnet M, Claus R, Becker N, Zucknick M, Petersen J, Lipka DB, Oakes CC, Andrulis M, Lier A, Milsom MD, Witte T, Gu L, Kim-Wanner SZ, Schirmacher P, Wulfert M, Gattermann N, Lübbert M, Rosenbauer F, Rehli M, Bullinger L, Weichenhan D, Plass C. Sonnet M, et al. Among authors: milsom md. Genome Med. 2014 Apr 30;6(4):34. doi: 10.1186/gm551. eCollection 2014. Genome Med. 2014. PMID: 24944583 Free PMC article.
68 results