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Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Brouwer JM, Lan P, Cowan AD, Bernardini JP, Birkinshaw RW, van Delft MF, Sleebs BE, Robin AY, Wardak A, Tan IK, Reljic B, Lee EF, Fairlie WD, Call MJ, Smith BJ, Dewson G, Lessene G, Colman PM, Czabotar PE. Brouwer JM, et al. Among authors: colman pm. Mol Cell. 2017 Nov 16;68(4):659-672.e9. doi: 10.1016/j.molcel.2017.11.001. Mol Cell. 2017. PMID: 29149594 Free article.
Structure-based drug design.
Colman PM. Colman PM. Curr Opin Struct Biol. 1994 Dec;4(6):868-74. doi: 10.1016/0959-440x(94)90268-2. Curr Opin Struct Biol. 1994. PMID: 7712290 Review.
Structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum.
Satchell JF, Malby RL, Luo CS, Adisa A, Alpyurek AE, Klonis N, Smith BJ, Tilley L, Colman PM. Satchell JF, et al. Among authors: colman pm. Acta Crystallogr D Biol Crystallogr. 2005 Sep;61(Pt 9):1213-21. doi: 10.1107/S0907444905018317. Epub 2005 Aug 16. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 16131754
148 results