Askin D - Search Results

1

Highly Efficient Synthesis of a Staphylococcus aureus Targeting Payload to Enable the First Antibody-Antibiotic Conjugate.

Linghu X, Segraves NL, Abramovich I, Wong N, Müller B, Neubauer N, Fantasia S, Rieth S, Bachmann S, Jansen M, Sowell CG, Askin D, Koenig SG, Gosselin F. Linghu X, et al. Among authors: askin d. Chemistry. 2018 Feb 26;24(12):2837-2840. doi: 10.1002/chem.201705392. Epub 2017 Dec 8. Chemistry. 2018. PMID: 29164727

2

Synthesis of a beta-amino acid pharmacophore via a beta-lactam intermediate.

Angelaud R, Zhong YL, Maligres P, Lee J, Askin D. Angelaud R, et al. Among authors: askin d. J Org Chem. 2005 Mar 4;70(5):1949-52. doi: 10.1021/jo048249c. J Org Chem. 2005. PMID: 15730331

3

Stereocontrolled preparation of a nonpeptidal (-)-spirobicyclic NK-1 receptor antagonist.

Maligres PE, Waters MM, Lee J, Reamer RA, Askin D, Ashwood MS, Cameron M. Maligres PE, et al. Among authors: askin d. J Org Chem. 2002 Feb 22;67(4):1093-101. doi: 10.1021/jo0157472. J Org Chem. 2002. PMID: 11846649

4

Catalytic asymmetric synthesis of an HIV integrase inhibitor.

Zhong YL, Krska SW, Zhou H, Reamer RA, Lee J, Sun Y, Askin D. Zhong YL, et al. Among authors: askin d. Org Lett. 2009 Jan 15;11(2):369-72. doi: 10.1021/ol802604v. Org Lett. 2009. PMID: 19099496

5

Practical synthesis of sultams via sulfonamide dianion alkylation: application to the synthesis of chiral sultams.

Lee J, Zhong YL, Reamer RA, Askin D. Lee J, et al. Among authors: askin d. Org Lett. 2003 Oct 30;5(22):4175-7. doi: 10.1021/ol0356183. Org Lett. 2003. PMID: 14572278

6

New method for the synthesis of diversely functionalized imidazoles from N-acylated alpha-aminonitriles.

Zhong YL, Lee J, Reamer RA, Askin D. Zhong YL, et al. Among authors: askin d. Org Lett. 2004 Mar 18;6(6):929-31. doi: 10.1021/ol036423y. Org Lett. 2004. PMID: 15012067

7

A polar radical pair pathway to assemble the pyrimidinone core of the HIV integrase inhibitor raltegravir potassium.

Pye PJ, Zhong YL, Jones GO, Reamer RA, Houk KN, Askin D. Pye PJ, et al. Among authors: askin d. Angew Chem Int Ed Engl. 2008;47(22):4134-6. doi: 10.1002/anie.200703681. Angew Chem Int Ed Engl. 2008. PMID: 18433071 No abstract available.

8

Porcine liver esterase-catalyzed enantioselective hydrolysis of a prochiral diester into its optically pure (S)-ester acid, a precursor to a growth hormone secretagogue.

Chartrain M, Maligres P, Cohen D, Upadhyay V, Pecore V, Askin D, Greasham R. Chartrain M, et al. Among authors: askin d. J Biosci Bioeng. 1999;87(3):386-9. doi: 10.1016/s1389-1723(99)80051-6. J Biosci Bioeng. 1999. PMID: 16232487

9

The synthesis of indinavir and other clinically useful HIV-1 protease inhibitors.

Askin D. Askin D. Curr Opin Drug Discov Devel. 1998 Nov;1(3):338-48. Curr Opin Drug Discov Devel. 1998. PMID: 19649808 No abstract available.

10

Kynurenine Pathway Dysregulation and Pain Perception in Acute Pancreatitis: Has the Connection Unraveled?

Cizmecioglu A, Eryavuz Onmaz D, Senturk S, Askin D, Unlu A, Korkmaz H, Gungor G. Cizmecioglu A, et al. Among authors: askin d. Neurosci Lett. 2024 Aug 10;837:137902. doi: 10.1016/j.neulet.2024.137902. Epub 2024 Jul 17. Neurosci Lett. 2024. PMID: 39029612

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