Nuhn L - Search Results

1

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

Van Herck S, Van Hoecke L, Louage B, Lybaert L, De Coen R, Kasmi S, Esser-Kahn AP, David SA, Nuhn L, Schepens B, Saelens X, De Geest BG. Van Herck S, et al. Among authors: nuhn l. Bioconjug Chem. 2018 Mar 21;29(3):748-760. doi: 10.1021/acs.bioconjchem.7b00641. Epub 2017 Dec 13. Bioconjug Chem. 2018. PMID: 29172458

2

Transiently thermoresponsive polymers and their applications in biomedicine.

Vanparijs N, Nuhn L, De Geest BG. Vanparijs N, et al. Among authors: nuhn l. Chem Soc Rev. 2017 Feb 20;46(4):1193-1239. doi: 10.1039/c6cs00748a. Chem Soc Rev. 2017. PMID: 28165097 Review.

3

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.

Nuhn L, Van Hoecke L, Deswarte K, Schepens B, Li Y, Lambrecht BN, De Koker S, David SA, Saelens X, De Geest BG. Nuhn L, et al. Biomaterials. 2018 Sep;178:643-651. doi: 10.1016/j.biomaterials.2018.03.026. Epub 2018 Mar 16. Biomaterials. 2018. PMID: 29573820

4

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation.

Nuhn L, Vanparijs N, De Beuckelaer A, Lybaert L, Verstraete G, Deswarte K, Lienenklaus S, Shukla NM, Salyer AC, Lambrecht BN, Grooten J, David SA, De Koker S, De Geest BG. Nuhn L, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8098-103. doi: 10.1073/pnas.1600816113. Epub 2016 Jul 5. Proc Natl Acad Sci U S A. 2016. PMID: 27382168 Free PMC article.

5

Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach.

Louage B, Nuhn L, Risseeuw MD, Vanparijs N, De Coen R, Karalic I, Van Calenbergh S, De Geest BG. Louage B, et al. Among authors: nuhn l. Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11791-6. doi: 10.1002/anie.201605892. Epub 2016 Aug 25. Angew Chem Int Ed Engl. 2016. PMID: 27560940

6

Targeting Protumoral Tumor-Associated Macrophages with Nanobody-Functionalized Nanogels through Strain Promoted Azide Alkyne Cycloaddition Ligation.

Nuhn L, Bolli E, Massa S, Vandenberghe I, Movahedi K, Devreese B, Van Ginderachter JA, De Geest BG. Nuhn L, et al. Bioconjug Chem. 2018 Jul 18;29(7):2394-2405. doi: 10.1021/acs.bioconjchem.8b00319. Epub 2018 Jun 28. Bioconjug Chem. 2018. PMID: 29889515

7

Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity.

Lybaert L, Vermaelen K, De Geest BG, Nuhn L. Lybaert L, et al. Among authors: nuhn l. J Control Release. 2018 Nov 10;289:125-145. doi: 10.1016/j.jconrel.2018.09.009. Epub 2018 Sep 14. J Control Release. 2018. PMID: 30223044 Review.

8

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses.

Nuhn L, De Koker S, Van Lint S, Zhong Z, Catani JP, Combes F, Deswarte K, Li Y, Lambrecht BN, Lienenklaus S, Sanders NN, David SA, Tavernier J, De Geest BG. Nuhn L, et al. Adv Mater. 2018 Nov;30(45):e1803397. doi: 10.1002/adma.201803397. Epub 2018 Oct 1. Adv Mater. 2018. PMID: 30276880

9

Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates.

Van Herck S, Deswarte K, Nuhn L, Zhong Z, Portela Catani JP, Li Y, Sanders NN, Lienenklaus S, De Koker S, Lambrecht BN, David SA, De Geest BG. Van Herck S, et al. Among authors: nuhn l. J Am Chem Soc. 2018 Oct 31;140(43):14300-14307. doi: 10.1021/jacs.8b08595. Epub 2018 Oct 17. J Am Chem Soc. 2018. PMID: 30277761

10

A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window.

Zhang Z, Li H, Kasmi S, Van Herck S, Deswarte K, Lambrecht BN, Hoogenboom R, Nuhn L, De Geest BG. Zhang Z, et al. Among authors: nuhn l. Angew Chem Int Ed Engl. 2019 Jun 3;58(23):7866-7872. doi: 10.1002/anie.201900224. Epub 2019 Apr 30. Angew Chem Int Ed Engl. 2019. PMID: 30925024

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