Ngwane A - Search Results

1

Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.

Morake M, Coertzen D, Ngwane A, Wentzel JF, Wong HN, Smit FJ, Birkholtz LM, Pietersen RD, Baker B, Wiid I, N'Da DD, Haynes RK. Morake M, et al. Among authors: ngwane a. ChemMedChem. 2018 Jan 8;13(1):67-77. doi: 10.1002/cmdc.201700579. Epub 2017 Dec 15. ChemMedChem. 2018. PMID: 29193799

2

The evaluation of the anti-cancer drug elesclomol that forms a redox-active copper chelate as a potential anti-tubercular drug.

Ngwane AH, Petersen RD, Baker B, Wiid I, Wong HN, Haynes RK. Ngwane AH, et al. IUBMB Life. 2019 May;71(5):532-538. doi: 10.1002/iub.2002. Epub 2019 Jan 14. IUBMB Life. 2019. PMID: 30698324 Free article.

3

Synthesis, antimycobacterial evaluation and pharmacophore modeling of analogues of the natural product formononetin.

Mutai P, Pavadai E, Wiid I, Ngwane A, Baker B, Chibale K. Mutai P, et al. Among authors: ngwane a. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2510-3. doi: 10.1016/j.bmcl.2015.04.064. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25977095

4

Anti-mycobacterium tuberculosis activity of polyherbal medicines used for the treatment of tuberculosis in Eastern Cape, South Africa.

Famewo EB, Clarke AM, Wiid I, Ngwane A, van Helden P, Afolayan AJ. Famewo EB, et al. Among authors: ngwane a. Afr Health Sci. 2017 Sep;17(3):780-789. doi: 10.4314/ahs.v17i3.21. Afr Health Sci. 2017. PMID: 29085406 Free PMC article.

5

Sulfamethoxazole enhances the antimycobacterial activity of rifampicin.

Macingwana L, Baker B, Ngwane AH, Harper C, Cotton MF, Hesseling A, Diacon AH, van Helden P, Wiid I. Macingwana L, et al. Among authors: ngwane ah. J Antimicrob Chemother. 2012 Dec;67(12):2908-11. doi: 10.1093/jac/dks306. Epub 2012 Aug 8. J Antimicrob Chemother. 2012. PMID: 22875849

6

Design, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives.

Ngwane AH, Panayides JL, Chouteau F, Macingwana L, Viljoen A, Baker B, Madikane E, de Kock C, Wiesner L, Chibale K, Parkinson CJ, Mmutlane EM, van Helden P, Wiid I. Ngwane AH, et al. IUBMB Life. 2016 Aug;68(8):612-20. doi: 10.1002/iub.1526. Epub 2016 Jun 27. IUBMB Life. 2016. PMID: 27346745 Free article.

7

Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis.

Kumar M, Singh K, Ngwane AH, Hamzabegovic F, Abate G, Baker B, Wiid I, Hoft DF, Ruminski P, Chibale K. Kumar M, et al. Among authors: ngwane ah. Bioorg Med Chem. 2018 Feb 15;26(4):833-844. doi: 10.1016/j.bmc.2017.12.047. Epub 2017 Dec 29. Bioorg Med Chem. 2018. PMID: 29373270

8

Proteomic analysis reveals that sulfamethoxazole induces oxidative stress in M. tuberculosis.

Sarkar R, Mdladla C, Macingwana L, Pietersen RD, Ngwane AH, Tabb DL, van Helden PD, Wiid I, Baker B. Sarkar R, et al. Among authors: ngwane ah. Tuberculosis (Edinb). 2018 Jul;111:78-85. doi: 10.1016/j.tube.2018.05.010. Epub 2018 May 17. Tuberculosis (Edinb). 2018. PMID: 30029919

9

Topical Delivery of Artemisone, Clofazimine and Decoquinate Encapsulated in Vesicles and Their In vitro Efficacy Against Mycobacterium tuberculosis.

van Zyl L, Viljoen JM, Haynes RK, Aucamp M, Ngwane AH, du Plessis J. van Zyl L, et al. Among authors: ngwane ah. AAPS PharmSciTech. 2019 Jan 2;20(1):33. doi: 10.1208/s12249-018-1251-5. AAPS PharmSciTech. 2019. PMID: 30604176

10

Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate.

Burger C, Aucamp M, du Preez J, Haynes RK, Ngwane A, du Plessis J, Gerber M. Burger C, et al. Among authors: ngwane a. Pharm Res. 2018 Aug 7;35(10):186. doi: 10.1007/s11095-018-2471-9. Pharm Res. 2018. PMID: 30088097

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