Tanguay RL - Search Results

1

Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.

Jang HS, Pearce M, O'Donnell EF, Nguyen BD, Truong L, Mueller MJ, Bisson WH, Kerkvliet NI, Tanguay RL, Kolluri SK. Jang HS, et al. Among authors: tanguay rl. Biology (Basel). 2017 Dec 1;6(4):41. doi: 10.3390/biology6040041. Biology (Basel). 2017. PMID: 29194351 Free PMC article.

2

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain.

Perkins A, Phillips JL, Kerkvliet NI, Tanguay RL, Perdew GH, Kolluri SK, Bisson WH. Perkins A, et al. Among authors: tanguay rl. Biology (Basel). 2014 Oct 17;3(4):645-69. doi: 10.3390/biology3040645. Biology (Basel). 2014. PMID: 25329374 Free PMC article.

3

Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.

Bisson WH, Koch DC, O'Donnell EF, Khalil SM, Kerkvliet NI, Tanguay RL, Abagyan R, Kolluri SK. Bisson WH, et al. Among authors: tanguay rl. J Med Chem. 2009 Sep 24;52(18):5635-41. doi: 10.1021/jm900199u. J Med Chem. 2009. PMID: 19719119 Free PMC article.

4

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.

O'Donnell EF, Saili KS, Koch DC, Kopparapu PR, Farrer D, Bisson WH, Mathew LK, Sengupta S, Kerkvliet NI, Tanguay RL, Kolluri SK. O'Donnell EF, et al. Among authors: tanguay rl. PLoS One. 2010 Oct 1;5(10):e13128. doi: 10.1371/journal.pone.0013128. PLoS One. 2010. PMID: 20957046 Free PMC article.

5

Evaluation of embryotoxicity using the zebrafish model.

Truong L, Harper SL, Tanguay RL. Truong L, et al. Among authors: tanguay rl. Methods Mol Biol. 2011;691:271-9. doi: 10.1007/978-1-60761-849-2_16. Methods Mol Biol. 2011. PMID: 20972759 Free PMC article.

6

Alternate glucocorticoid receptor ligand binding structures influence outcomes in an in vivo tissue regeneration model.

Sengupta S, Bisson WH, Mathew LK, Kolluri SK, Tanguay RL. Sengupta S, et al. Among authors: tanguay rl. Comp Biochem Physiol C Toxicol Pharmacol. 2012 Aug;156(2):121-9. doi: 10.1016/j.cbpc.2012.05.003. Epub 2012 May 24. Comp Biochem Physiol C Toxicol Pharmacol. 2012. PMID: 22634227 Free PMC article.

7

The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.

O'Donnell EF, Kopparapu PR, Koch DC, Jang HS, Phillips JL, Tanguay RL, Kerkvliet NI, Kolluri SK. O'Donnell EF, et al. Among authors: tanguay rl. PLoS One. 2012;7(7):e40926. doi: 10.1371/journal.pone.0040926. Epub 2012 Jul 17. PLoS One. 2012. PMID: 22815870 Free PMC article.

8

Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.

Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL. Gerlach CV, et al. Among authors: tanguay rl. Aquat Toxicol. 2014 Sep;154:71-9. doi: 10.1016/j.aquatox.2014.05.007. Epub 2014 May 16. Aquat Toxicol. 2014. PMID: 24865613 Free PMC article.

9

Better, Faster, Cheaper: Getting the Most Out of High-Throughput Screening with Zebrafish.

Truong L, Simonich MT, Tanguay RL. Truong L, et al. Among authors: tanguay rl. Methods Mol Biol. 2016;1473:89-98. doi: 10.1007/978-1-4939-6346-1_10. Methods Mol Biol. 2016. PMID: 27518627

10

Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs.

Chlebowski AC, Garcia GR, La Du JK, Bisson WH, Truong L, Massey Simonich SL, Tanguay RL. Chlebowski AC, et al. Among authors: tanguay rl. Toxicol Sci. 2017 May 1;157(1):246-259. doi: 10.1093/toxsci/kfx035. Toxicol Sci. 2017. PMID: 28186253 Free PMC article.

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