Chen Y - Search Results

1

Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer.

Guo Y, Zhao Y, Wang G, Chen Y, Jiang Y, Ouyang L, Liu B. Guo Y, et al. Among authors: chen y. Eur J Med Chem. 2018 Jan 1;143:402-418. doi: 10.1016/j.ejmech.2017.11.065. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202403

2

Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors.

Xu T, Sun D, Chen Y, Ouyang L. Xu T, et al. Among authors: chen y. Eur J Med Chem. 2020 Aug 1;199:112391. doi: 10.1016/j.ejmech.2020.112391. Epub 2020 May 4. Eur J Med Chem. 2020. PMID: 32416459 Review.

3

Targeting Atg4B for cancer therapy: Chemical mediators.

Yang G, Li Y, Zhao Y, Ouyang L, Chen Y, Liu B, Liu J. Yang G, et al. Among authors: chen y. Eur J Med Chem. 2021 Jan 1;209:112917. doi: 10.1016/j.ejmech.2020.112917. Epub 2020 Oct 11. Eur J Med Chem. 2021. PMID: 33077263 Review.

4

Inhibiting Eukaryotic Elongation Factor 2 Kinase: An Update on Pharmacological Small-Molecule Compounds in Cancer.

Zhu S, Liao M, Tan H, Zhu L, Chen Y, He G, Liu B. Zhu S, et al. Among authors: chen y. J Med Chem. 2021 Jul 8;64(13):8870-8883. doi: 10.1021/acs.jmedchem.0c02218. Epub 2021 Jun 23. J Med Chem. 2021. PMID: 34162208 Review.

5

Dual-target inhibitors of bromodomain and extra-terminal proteins in cancer: A review from medicinal chemistry perspectives.

Feng L, Wang G, Chen Y, He G, Liu B, Liu J, Chiang CM, Ouyang L. Feng L, et al. Among authors: chen y. Med Res Rev. 2022 Mar;42(2):710-743. doi: 10.1002/med.21859. Epub 2021 Oct 11. Med Res Rev. 2022. PMID: 34633088 Free PMC article. Review.

6

Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for NTRK fusion cancers.

Jiang T, Wang G, Liu Y, Feng L, Wang M, Liu J, Chen Y, Ouyang L. Jiang T, et al. Among authors: chen y. Acta Pharm Sin B. 2021 Feb;11(2):355-372. doi: 10.1016/j.apsb.2020.05.004. Epub 2020 May 23. Acta Pharm Sin B. 2021. PMID: 33643817 Free PMC article. Review.

7

Targeting regulated cell death (RCD) with small-molecule compounds in cancer therapy: A revisited review of apoptosis, autophagy-dependent cell death and necroptosis.

Liu W, Jin W, Zhu S, Chen Y, Liu B. Liu W, et al. Among authors: chen y. Drug Discov Today. 2022 Feb;27(2):612-625. doi: 10.1016/j.drudis.2021.10.011. Epub 2021 Oct 27. Drug Discov Today. 2022. PMID: 34718209 Review.

8

Designing strategies of small-molecule compounds for modulating non-coding RNAs in cancer therapy.

Zhao R, Fu J, Zhu L, Chen Y, Liu B. Zhao R, et al. Among authors: chen y. J Hematol Oncol. 2022 Feb 5;15(1):14. doi: 10.1186/s13045-022-01230-6. J Hematol Oncol. 2022. PMID: 35123522 Free PMC article. Review.

9

Unraveling the Roles of Protein Kinases in Autophagy: An Update on Small-Molecule Compounds for Targeted Therapy.

Fu J, Yang Y, Zhu L, Chen Y, Liu B. Fu J, et al. Among authors: chen y. J Med Chem. 2022 Apr 28;65(8):5870-5885. doi: 10.1021/acs.jmedchem.1c02053. Epub 2022 Apr 7. J Med Chem. 2022. PMID: 35390258 Review.

10

Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.

Fu L, Chen S, He G, Chen Y, Liu B. Fu L, et al. Among authors: chen s, chen y. J Med Chem. 2022 Oct 27;65(20):13561-13573. doi: 10.1021/acs.jmedchem.2c01244. Epub 2022 Oct 7. J Med Chem. 2022. PMID: 36205714 Review.

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