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Page 1
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Among authors: kleinstreuer nc. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
Knudsen TB, Houck KA, Sipes NS, Singh AV, Judson RS, Martin MT, Weissman A, Kleinstreuer NC, Mortensen HM, Reif DM, Rabinowitz JR, Setzer RW, Richard AM, Dix DJ, Kavlock RJ. Knudsen TB, et al. Among authors: kleinstreuer nc. Toxicology. 2011 Mar 28;282(1-2):1-15. doi: 10.1016/j.tox.2010.12.010. Epub 2011 Jan 18. Toxicology. 2011. PMID: 21251949
Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay.
Chandler KJ, Barrier M, Jeffay S, Nichols HP, Kleinstreuer NC, Singh AV, Reif DM, Sipes NS, Judson RS, Dix DJ, Kavlock R, Hunter ES 3rd, Knudsen TB. Chandler KJ, et al. Among authors: kleinstreuer nc. PLoS One. 2011;6(6):e18540. doi: 10.1371/journal.pone.0018540. Epub 2011 Jun 7. PLoS One. 2011. PMID: 21666745 Free PMC article.
Predictive models and computational toxicology.
Knudsen T, Martin M, Chandler K, Kleinstreuer N, Judson R, Sipes N. Knudsen T, et al. Methods Mol Biol. 2013;947:343-74. doi: 10.1007/978-1-62703-131-8_26. Methods Mol Biol. 2013. PMID: 23138916 Review.
A computational model predicting disruption of blood vessel development.
Kleinstreuer N, Dix D, Rountree M, Baker N, Sipes N, Reif D, Spencer R, Knudsen T. Kleinstreuer N, et al. PLoS Comput Biol. 2013 Apr;9(4):e1002996. doi: 10.1371/journal.pcbi.1002996. Epub 2013 Apr 4. PLoS Comput Biol. 2013. PMID: 23592958 Free PMC article.
155 results