Clevers H - Search Results

1

Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.

Jager M, Blokzijl F, Sasselli V, Boymans S, Janssen R, Besselink N, Clevers H, van Boxtel R, Cuppen E. Jager M, et al. Among authors: clevers h. Nat Protoc. 2018 Jan;13(1):59-78. doi: 10.1038/nprot.2017.111. Epub 2017 Dec 7. Nat Protoc. 2018. PMID: 29215633

2

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4.

Schilham MW, Oosterwegel MA, Moerer P, Ya J, de Boer PA, van de Wetering M, Verbeek S, Lamers WH, Kruisbeek AM, Cumano A, Clevers H. Schilham MW, et al. Among authors: clevers h. Nature. 1996 Apr 25;380(6576):711-4. doi: 10.1038/380711a0. Nature. 1996. PMID: 8614465

3

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: clevers h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.

4

Identification of stem cells in small intestine and colon by marker gene Lgr5.

Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Barker N, et al. Among authors: clevers h. Nature. 2007 Oct 25;449(7165):1003-7. doi: 10.1038/nature06196. Epub 2007 Oct 14. Nature. 2007. PMID: 17934449

5

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.

Hatzis P, van der Flier LG, van Driel MA, Guryev V, Nielsen F, Denissov S, Nijman IJ, Koster J, Santo EE, Welboren W, Versteeg R, Cuppen E, van de Wetering M, Clevers H, Stunnenberg HG. Hatzis P, et al. Among authors: clevers h. Mol Cell Biol. 2008 Apr;28(8):2732-44. doi: 10.1128/MCB.02175-07. Epub 2008 Feb 11. Mol Cell Biol. 2008. PMID: 18268006 Free PMC article.

6

Crypt stem cells as the cells-of-origin of intestinal cancer.

Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H. Barker N, et al. Among authors: clevers h. Nature. 2009 Jan 29;457(7229):608-11. doi: 10.1038/nature07602. Epub 2008 Dec 17. Nature. 2009. PMID: 19092804

7

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Sato T, et al. Among authors: clevers h. Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29. Nature. 2009. PMID: 19329995

8

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

Begus-Nahrmann Y, Lechel A, Obenauf AC, Nalapareddy K, Peit E, Hoffmann E, Schlaudraff F, Liss B, Schirmacher P, Kestler H, Danenberg E, Barker N, Clevers H, Speicher MR, Rudolph KL. Begus-Nahrmann Y, et al. Among authors: clevers h. Nat Genet. 2009 Oct;41(10):1138-43. doi: 10.1038/ng.426. Epub 2009 Aug 30. Nat Genet. 2009. PMID: 19718028

9

In situ hybridization to identify gut stem cells.

Gregorieff A, Clevers H. Gregorieff A, et al. Among authors: clevers h. Curr Protoc Stem Cell Biol. 2010 Jan;Chapter 2:Unit 2F.1. doi: 10.1002/9780470151808.sc02f01s12. Curr Protoc Stem Cell Biol. 2010. PMID: 20049690

10

Searching for adult stem cells in the intestine.

Clevers H. Clevers H. EMBO Mol Med. 2009 Aug;1(5):255-9. doi: 10.1002/emmm.200900034. EMBO Mol Med. 2009. PMID: 20049728 Free PMC article. No abstract available.

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