Tunes LG - Search Results

1

Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood).

Cota BB, Tunes LG, Maia DNB, Ramos JP, Oliveira DM, Kohlhoff M, Alves TMA, Souza-Fagundes EM, Campos FF, Zani CL. Cota BB, et al. Among authors: tunes lg. Mem Inst Oswaldo Cruz. 2018 Feb;113(2):102-110. doi: 10.1590/0074-02760170217. Mem Inst Oswaldo Cruz. 2018. PMID: 29236928 Free PMC article.

2

Trypanocidal Trixikingolides From Trixis Vauthieri.

Sales Junior PA, Zani CL, de Siqueira EP, Kohlhoff M, Marques FR, Caldeira ASP, Cota BB, Maia DNB, Tunes LG, Murta SMF, Alves TMA. Sales Junior PA, et al. Among authors: tunes lg. Nat Prod Res. 2021 Aug;35(16):2691-2699. doi: 10.1080/14786419.2019.1663510. Epub 2019 Sep 18. Nat Prod Res. 2021. PMID: 31530021

3

Novel gold(I) complexes with 5-phenyl-1,3,4-oxadiazole-2-thione and phosphine as potential anticancer and antileishmanial agents.

Chaves JDS, Tunes LG, de J Franco CH, Francisco TM, Corrêa CC, Murta SMF, Monte-Neto RL, Silva H, Fontes APS, de Almeida MV. Chaves JDS, et al. Among authors: tunes lg. Eur J Med Chem. 2017 Feb 15;127:727-739. doi: 10.1016/j.ejmech.2016.10.052. Epub 2016 Oct 24. Eur J Med Chem. 2017. PMID: 27823888

4

Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4-oxadiazole-2(3H)-thione ligands derived from δ-D-gluconolactone.

Espinosa AV, Costa DS, Tunes LG, Monte-Neto RLD, Grazul RM, de Almeida MV, Silva H. Espinosa AV, et al. Among authors: tunes lg. Chem Biol Drug Des. 2021 Jan;97(1):41-50. doi: 10.1111/cbdd.13757. Epub 2020 Jul 26. Chem Biol Drug Des. 2021. PMID: 32657521

5

Unveiling six potent and highly selective antileishmanial agents via the open source compound collection 'Pathogen Box' against antimony-sensitive and -resistant Leishmania braziliensis.

Souza Silva JA, Tunes LG, Coimbra RS, Ascher DB, Pires DEV, Monte-Neto RL. Souza Silva JA, et al. Among authors: tunes lg. Biomed Pharmacother. 2021 Jan;133:111049. doi: 10.1016/j.biopha.2020.111049. Epub 2020 Dec 4. Biomed Pharmacother. 2021. PMID: 33378956 Free article.

6

Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors.

Tunes LG, Morato RE, Garcia A, Schmitz V, Steindel M, Corrêa-Junior JD, Dos Santos HF, Frézard F, de Almeida MV, Silva H, Moretti NS, de Barros ALB, do Monte-Neto RL. Tunes LG, et al. ACS Infect Dis. 2020 May 8;6(5):1121-1139. doi: 10.1021/acsinfecdis.9b00505. Epub 2020 Apr 27. ACS Infect Dis. 2020. PMID: 32283915

7

Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice.

Santi AMM, Lanza JS, Tunes LG, Fiuza JA, Roy G, Orfanó ADS, de Carvalho AT, Frézard F, Barros ALB, Murta SMF, do Monte-Neto RL. Santi AMM, et al. Among authors: tunes lg. Sci Rep. 2018 Aug 2;8(1):11627. doi: 10.1038/s41598-018-30076-7. Sci Rep. 2018. PMID: 30072701 Free PMC article.

8

The mutation G133D on Leishmania guyanensis AQP1 is highly destabilizing as revealed by molecular modeling and hypo-osmotic shock assay.

Tunes LG, Ascher DB, Pires DEV, Monte-Neto RL. Tunes LG, et al. Biochim Biophys Acta Biomembr. 2021 Oct 1;1863(10):183682. doi: 10.1016/j.bbamem.2021.183682. Epub 2021 Jun 24. Biochim Biophys Acta Biomembr. 2021. PMID: 34175297 Free article.

9

Changes in antiparasitical activity of gold nanorods according to the chosen synthesis.

Lage ACP, Ladeira LO, do Camo PHF, Amorim JM, Monte-Neto RL, Santos DA, Tunes LG, Castilho RO, Moreira PO, Ferreira DC, Lopez Silva DE, Gomes Faraco AA. Lage ACP, et al. Among authors: tunes lg. Exp Parasitol. 2022 Nov;242:108367. doi: 10.1016/j.exppara.2022.108367. Epub 2022 Aug 31. Exp Parasitol. 2022. PMID: 36055388

10

Planarians as models to investigate the bioactivity of gold(I) complexes in vivo.

Tunes LG, Allen JM, Zayas RM, do Monte-Neto RL. Tunes LG, et al. Sci Rep. 2018 Nov 1;8(1):16180. doi: 10.1038/s41598-018-34558-6. Sci Rep. 2018. PMID: 30385794 Free PMC article.

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