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Page 1
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.
Robinson JI, Baxter EW, Owen RL, Thomsen M, Tomlinson DC, Waterhouse MP, Win SJ, Nettleship JE, Tiede C, Foster RJ, Owens RJ, Fishwick CWG, Harris SA, Goldman A, McPherson MJ, Morgan AW. Robinson JI, et al. Among authors: morgan aw. Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E72-E81. doi: 10.1073/pnas.1707856115. Epub 2017 Dec 15. Proc Natl Acad Sci U S A. 2018. PMID: 29247053 Free PMC article.
Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.
Willcocks LC, Lyons PA, Clatworthy MR, Robinson JI, Yang W, Newland SA, Plagnol V, McGovern NN, Condliffe AM, Chilvers ER, Adu D, Jolly EC, Watts R, Lau YL, Morgan AW, Nash G, Smith KG. Willcocks LC, et al. Among authors: morgan aw. J Exp Med. 2008 Jul 7;205(7):1573-82. doi: 10.1084/jem.20072413. Epub 2008 Jun 16. J Exp Med. 2008. PMID: 18559452 Free PMC article.
Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.
Coulthard LR, Taylor JC, Eyre S; Biologics in Rheumatoid Arthritis Genetics and Genomics; Robinson JI, Wilson AG, Isaacs JD, Hyrich K, Emery P, Barton A, Barrett JH, Morgan AW, McDermott MF. Coulthard LR, et al. Among authors: morgan aw. Ann Rheum Dis. 2011 Jan;70(1):98-103. doi: 10.1136/ard.2010.133249. Epub 2010 Aug 30. Ann Rheum Dis. 2011. PMID: 20805296
In situ macromolecular crystallography using microbeams.
Axford D, Owen RL, Aishima J, Foadi J, Morgan AW, Robinson JI, Nettleship JE, Owens RJ, Moraes I, Fry EE, Grimes JM, Harlos K, Kotecha A, Ren J, Sutton G, Walter TS, Stuart DI, Evans G. Axford D, et al. Among authors: morgan aw. Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):592-600. doi: 10.1107/S0907444912006749. Epub 2012 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22525757 Free PMC article.
Outrunning free radicals in room-temperature macromolecular crystallography.
Owen RL, Axford D, Nettleship JE, Owens RJ, Robinson JI, Morgan AW, Doré AS, Lebon G, Tate CG, Fry EE, Ren J, Stuart DI, Evans G. Owen RL, et al. Among authors: morgan aw. Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):810-8. doi: 10.1107/S0907444912012553. Epub 2012 Jun 15. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22751666 Free PMC article.
Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.
Morgan AW, Robinson JI, Conaghan PG, Martin SG, Hensor EM, Morgan MD, Steiner L, Erlich HA, Gooi HC, Barton A, Worthington J, Emery P; UKRAG Consortium; YEAR Consortium. Morgan AW, et al. Among authors: morgan md. Arthritis Res Ther. 2010;12(2):R57. doi: 10.1186/ar2969. Epub 2010 Mar 30. Arthritis Res Ther. 2010. PMID: 20353580 Free PMC article.
174 results