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139 results

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SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia.
Bu J, Chen A, Yan X, He F, Dong Y, Zhou Y, He J, Zhan D, Lin P, Hayashi Y, Sun Y, Zhang Y, Xiao Z, Grimes HL, Wang QF, Huang G. Bu J, et al. Among authors: grimes hl. Leukemia. 2018 Apr;32(4):890-899. doi: 10.1038/leu.2017.339. Epub 2017 Nov 29. Leukemia. 2018. PMID: 29249820 Free PMC article.
Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells.
Zhang Y, Yan X, Sashida G, Zhao X, Rao Y, Goyama S, Whitman SP, Zorko N, Bernot K, Conway RM, Witte D, Wang QF, Tenen DG, Xiao Z, Marcucci G, Mulloy JC, Grimes HL, Caligiuri MA, Huang G. Zhang Y, et al. Among authors: grimes hl. Blood. 2012 Aug 2;120(5):1118-29. doi: 10.1182/blood-2012-02-412379. Epub 2012 Jun 26. Blood. 2012. PMID: 22740449 Free PMC article.
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells.
Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link KA, Mizukawa B, Grimes HL, Kurokawa M, Liu PP, Huang G, Mulloy JC. Goyama S, et al. Among authors: grimes hl. J Clin Invest. 2013 Sep;123(9):3876-88. doi: 10.1172/JCI68557. Epub 2013 Aug 27. J Clin Invest. 2013. PMID: 23979164 Free PMC article.
Enhanced MAPK signaling is essential for CSF3R-induced leukemia.
Rohrabaugh S, Kesarwani M, Kincaid Z, Huber E, Leddonne J, Siddiqui Z, Khalifa Y, Komurov K, Grimes HL, Azam M. Rohrabaugh S, et al. Among authors: grimes hl. Leukemia. 2017 Aug;31(8):1770-1778. doi: 10.1038/leu.2016.376. Epub 2016 Dec 27. Leukemia. 2017. PMID: 28031554 Free PMC article.
Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation.
Zhou Y, Yan X, Feng X, Bu J, Dong Y, Lin P, Hayashi Y, Huang R, Olsson A, Andreassen PR, Grimes HL, Wang QF, Cheng T, Xiao Z, Jin J, Huang G. Zhou Y, et al. Among authors: grimes hl. Haematologica. 2018 Jul;103(7):1110-1123. doi: 10.3324/haematol.2018.187708. Epub 2018 Apr 12. Haematologica. 2018. PMID: 29650642 Free PMC article.
Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.
Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G. Hayashi Y, et al. Among authors: grimes hl. Cancer Discov. 2018 Nov;8(11):1438-1457. doi: 10.1158/2159-8290.CD-17-1203. Epub 2018 Aug 23. Cancer Discov. 2018. PMID: 30139811 Free PMC article.
139 results