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Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
Bassani-Sternberg M, Bräunlein E, Klar R, Engleitner T, Sinitcyn P, Audehm S, Straub M, Weber J, Slotta-Huspenina J, Specht K, Martignoni ME, Werner A, Hein R, H Busch D, Peschel C, Rad R, Cox J, Mann M, Krackhardt AM. Bassani-Sternberg M, et al. Among authors: krackhardt am. Nat Commun. 2016 Nov 21;7:13404. doi: 10.1038/ncomms13404. Nat Commun. 2016. PMID: 27869121 Free PMC article.
Tools to define the melanoma-associated immunopeptidome.
Bräunlein E, Krackhardt AM. Bräunlein E, et al. Among authors: krackhardt am. Immunology. 2017 Dec;152(4):536-544. doi: 10.1111/imm.12803. Epub 2017 Aug 28. Immunology. 2017. PMID: 28755382 Free PMC article. Review.
T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target.
Mayer KE, Mall S, Yusufi N, Gosmann D, Steiger K, Russelli L, Bianchi HO, Audehm S, Wagner R, Bräunlein E, Stelzl A, Bassermann F, Weichert W, Weber W, Schwaiger M, D'Alessandria C, Krackhardt AM. Mayer KE, et al. Among authors: krackhardt am. Theranostics. 2018 Nov 28;8(21):6070-6087. doi: 10.7150/thno.27275. eCollection 2018. Theranostics. 2018. PMID: 30613283 Free PMC article.
Key Features Relevant to Select Antigens and TCR From the MHC-Mismatched Repertoire to Treat Cancer.
Audehm S, Glaser M, Pecoraro M, Bräunlein E, Mall S, Klar R, Effenberger M, Albers J, Bianchi HO, Peper J, Yusufi N, Busch DH, Stevanović S, Mann M, Antes I, Krackhardt AM. Audehm S, et al. Among authors: krackhardt am. Front Immunol. 2019 Jun 28;10:1485. doi: 10.3389/fimmu.2019.01485. eCollection 2019. Front Immunol. 2019. PMID: 31316521 Free PMC article.
Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Wilhelm M, Zolg DP, Graber M, Gessulat S, Schmidt T, Schnatbaum K, Schwencke-Westphal C, Seifert P, de Andrade Krätzig N, Zerweck J, Knaute T, Bräunlein E, Samaras P, Lautenbacher L, Klaeger S, Wenschuh H, Rad R, Delanghe B, Huhmer A, Carr SA, Clauser KR, Krackhardt AM, Reimer U, Kuster B. Wilhelm M, et al. Among authors: krackhardt am. Nat Commun. 2021 Jun 7;12(1):3346. doi: 10.1038/s41467-021-23713-9. Nat Commun. 2021. PMID: 34099720 Free PMC article.
Author Correction: Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Wilhelm M, Zolg DP, Graber M, Gessulat S, Schmidt T, Schnatbaum K, Schwencke-Westphal C, Seifert P, de Andrade Krätzig N, Zerweck J, Knaute T, Bräunlein E, Samaras P, Lautenbacher L, Klaeger S, Wenschuh H, Rad R, Delanghe B, Huhmer A, Carr SA, Clauser KR, Krackhardt AM, Reimer U, Kuster B. Wilhelm M, et al. Among authors: krackhardt am. Nat Commun. 2021 Jun 23;12(1):4002. doi: 10.1038/s41467-021-24263-w. Nat Commun. 2021. PMID: 34162890 Free PMC article. No abstract available.
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma.
Bräunlein E, Lupoli G, Füchsl F, Abualrous ET, de Andrade Krätzig N, Gosmann D, Wietbrock L, Lange S, Engleitner T, Lan H, Audehm S, Effenberger M, Boxberg M, Steiger K, Chang Y, Yu K, Atay C, Bassermann F, Weichert W, Busch DH, Rad R, Freund C, Antes I, Krackhardt AM. Bräunlein E, et al. Among authors: krackhardt am. J Immunother Cancer. 2021 Sep;9(9):e002754. doi: 10.1136/jitc-2021-002754. J Immunother Cancer. 2021. PMID: 34518289 Free PMC article.
66 results