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CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.
Jia J, Bosley AD, Thompson A, Hoskins JW, Cheuk A, Collins I, Parikh H, Xiao Z, Ylaya K, Dzyadyk M, Cozen W, Hernandez BY, Lynch CF, Loncarek J, Altekruse SF, Zhang L, Westlake CJ, Factor VM, Thorgeirsson S, Bamlet WR, Hewitt SM, Petersen GM, Andresson T, Amundadottir LT. Jia J, et al. Among authors: westlake cj. Cancer Res. 2014 May 15;74(10):2785-95. doi: 10.1158/0008-5472.CAN-13-3176. Epub 2014 Mar 19. Cancer Res. 2014. PMID: 24648346 Free PMC article.
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Lu Q, Insinna C, Ott C, Stauffer J, Pintado PA, Rahajeng J, Baxa U, Walia V, Cuenca A, Hwang YS, Daar IO, Lopes S, Lippincott-Schwartz J, Jackson PK, Caplan S, Westlake CJ. Lu Q, et al. Among authors: westlake cj. Nat Cell Biol. 2015 Mar;17(3):228-240. doi: 10.1038/ncb3109. Epub 2015 Feb 16. Nat Cell Biol. 2015. PMID: 25686250 Free PMC article.
Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.
Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, Ritt DA, Semler E, Specht S, Stauffer J, Morrison DK, Lorentzen E, Westlake CJ. Walia V, et al. Among authors: westlake cj. Dev Cell. 2019 Jul 22;50(2):229-246.e7. doi: 10.1016/j.devcel.2019.05.022. Epub 2019 Jun 13. Dev Cell. 2019. PMID: 31204173 Free PMC article.
The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.
Cuenca A, Insinna C, Zhao H, John P, Weiss MA, Lu Q, Walia V, Specht S, Manivannan S, Stauffer J, Peden AA, Westlake CJ. Cuenca A, et al. Among authors: westlake cj. J Biol Chem. 2019 Oct 18;294(42):15418-15434. doi: 10.1074/jbc.RA119.008615. Epub 2019 Aug 29. J Biol Chem. 2019. PMID: 31467083 Free PMC article.
49 results