Fishwick CWG - Search Results

1

In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.

Cain R, Brem J, Zollman D, McDonough MA, Johnson RM, Spencer J, Makena A, Abboud MI, Cahill S, Lee SY, McHugh PJ, Schofield CJ, Fishwick CWG. Cain R, et al. Among authors: fishwick cwg. J Med Chem. 2018 Feb 8;61(3):1255-1260. doi: 10.1021/acs.jmedchem.7b01728. Epub 2018 Jan 10. J Med Chem. 2018. PMID: 29271657 Free article.

2

From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma.

Lykins J, Moschitto MJ, Zhou Y, Filippova EV, Le HV, Tomita T, Fox BA, Bzik DJ, Su C, Rajagopala SV, Flores K, Spano F, Woods S, Roberts CW, Hua C, El Bissati K, Wheeler KM, Dovgin S, Muench SP, McPhillie M, Fishwick CWG, Anderson WF, Lee PJ, Hickman M, Weiss LM, Dubey JP, Lorenzi HA, Silverman RB, McLeod RL. Lykins J, et al. Among authors: fishwick cwg. iScience. 2023 Nov 16;27(1):108477. doi: 10.1016/j.isci.2023.108477. eCollection 2024 Jan 19. iScience. 2023. PMID: 38205261 Free PMC article.

3

Spatial requirements of the antagonist binding site of the NK2 receptor.

Ali MA, Bhogal N, Fishwick CW, Findlay JB. Ali MA, et al. Bioorg Med Chem Lett. 2001 Mar 26;11(6):819-22. doi: 10.1016/s0960-894x(01)00074-9. Bioorg Med Chem Lett. 2001. PMID: 11277528

4

Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD.

Horton JR, Bostock JM, Chopra I, Hesse L, Phillips SE, Adams DJ, Johnson AP, Fishwick CW. Horton JR, et al. Bioorg Med Chem Lett. 2003 May 5;13(9):1557-60. doi: 10.1016/s0960-894x(03)00176-8. Bioorg Med Chem Lett. 2003. PMID: 12699754

5

The first de novo-designed antagonists of the human NK(2) receptor.

Ali MA, Bhogal N, Findlay JB, Fishwick CW. Ali MA, et al. J Med Chem. 2005 Sep 8;48(18):5655-8. doi: 10.1021/jm050533o. J Med Chem. 2005. PMID: 16134933

6

The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

Heikkilä T, Thirumalairajan S, Davies M, Parsons MR, McConkey AG, Fishwick CW, Johnson AP. Heikkilä T, et al. Bioorg Med Chem Lett. 2006 Jan 1;16(1):88-92. doi: 10.1016/j.bmcl.2005.09.045. Epub 2005 Oct 19. Bioorg Med Chem Lett. 2006. PMID: 16236496

7

Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.

Heikkilä T, Ramsey C, Davies M, Galtier C, Stead AM, Johnson AP, Fishwick CW, Boa AN, McConkey GA. Heikkilä T, et al. J Med Chem. 2007 Jan 25;50(2):186-91. doi: 10.1021/jm060687j. J Med Chem. 2007. PMID: 17228860

8

2-Aminotetralones: novel inhibitors of MurA and MurZ.

Dunsmore CJ, Miller K, Blake KL, Patching SG, Henderson PJ, Garnett JA, Stubbings WJ, Phillips SE, Palestrant DJ, Angeles Jde L, Leeds JA, Chopra I, Fishwick CW. Dunsmore CJ, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1730-4. doi: 10.1016/j.bmcl.2008.01.089. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18261901

9

Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.

Davies M, Heikkilä T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Davies M, et al. J Med Chem. 2009 May 14;52(9):2683-93. doi: 10.1021/jm800963t. J Med Chem. 2009. PMID: 19351152

10

Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.

Yi Mok N, Chadwick J, Kellett KA, Hooper NM, Johnson AP, Fishwick CW. Yi Mok N, et al. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6770-4. doi: 10.1016/j.bmcl.2009.09.103. Epub 2009 Oct 2. Bioorg Med Chem Lett. 2009. PMID: 19854048

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