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Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.
Gao Y, Vasilyev DV, Goncalves MB, Howell FV, Hobbs C, Reisenberg M, Shen R, Zhang MY, Strassle BW, Lu P, Mark L, Piesla MJ, Deng K, Kouranova EV, Ring RH, Whiteside GT, Bates B, Walsh FS, Williams G, Pangalos MN, Samad TA, Doherty P. Gao Y, et al. Among authors: hobbs c. J Neurosci. 2010 Feb 10;30(6):2017-24. doi: 10.1523/JNEUROSCI.5693-09.2010. J Neurosci. 2010. PMID: 20147530 Free PMC article.
Neuronal RARβ Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration.
Goncalves MB, Malmqvist T, Clarke E, Hubens CJ, Grist J, Hobbs C, Trigo D, Risling M, Angeria M, Damberg P, Carlstedt TP, Corcoran JP. Goncalves MB, et al. Among authors: hobbs c. J Neurosci. 2015 Nov 25;35(47):15731-45. doi: 10.1523/JNEUROSCI.1339-15.2015. J Neurosci. 2015. PMID: 26609164 Free PMC article.
Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury.
Goncalves MB, Clarke E, Jarvis CI, Barret Kalindjian S, Pitcher T, Grist J, Hobbs C, Carlstedt T, Jack J, Brown JT, Mills M, Mumford P, Borthwick AD, Corcoran JPT. Goncalves MB, et al. Among authors: hobbs c. Bioorg Med Chem Lett. 2019 Apr 15;29(8):995-1000. doi: 10.1016/j.bmcl.2019.02.011. Epub 2019 Feb 11. Bioorg Med Chem Lett. 2019. PMID: 30792038 Free PMC article.
Corrigendum to "Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury" [Bioorg. Med. Chem. Lett. 29(8) (2019) 995-1000].
Goncalves MB, Clarke E, Jarvis CI, Kalindjian SB, Pitcher T, Grist J, Hobbs C, Carlstedt T, Jack J, Brown JT, Mills M, Mumford P, Borthwick AD, Corcoran JPT. Goncalves MB, et al. Among authors: hobbs c. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2440-2441. doi: 10.1016/j.bmcl.2019.05.058. Epub 2019 Jun 14. Bioorg Med Chem Lett. 2019. PMID: 31208764 Free PMC article. No abstract available.
C286, an orally available retinoic acid receptor β agonist drug, regulates multiple pathways to achieve spinal cord injury repair.
Goncalves MB, Wu Y, Clarke E, Grist J, Moehlin J, Mendoza-Parra MA, Hobbs C, Kalindjian B, Fok H, Mander AP, Hassanin H, Bendel D, Täubel J, Mant T, Carlstedt T, Jack J, Corcoran JPT. Goncalves MB, et al. Among authors: hobbs c. Front Mol Neurosci. 2024 Aug 20;17:1411384. doi: 10.3389/fnmol.2024.1411384. eCollection 2024. Front Mol Neurosci. 2024. PMID: 39228795 Free PMC article.
760 results