Knowles TPJ - Search Results

1

Charmet J, Arosio P, Knowles TPJ. Charmet J, et al. Among authors: knowles tpj. J Mol Biol. 2018 Mar 2;430(5):565-580. doi: 10.1016/j.jmb.2017.12.015. Epub 2017 Dec 29. J Mol Biol. 2018. PMID: 29289566 Review.

2

The component polypeptide chains of bovine insulin nucleate or inhibit aggregation of the parent protein in a conformation-dependent manner.

Devlin GL, Knowles TP, Squires A, McCammon MG, Gras SL, Nilsson MR, Robinson CV, Dobson CM, MacPhee CE. Devlin GL, et al. J Mol Biol. 2006 Jul 7;360(2):497-509. doi: 10.1016/j.jmb.2006.05.007. Epub 2006 May 17. J Mol Biol. 2006. PMID: 16774767

3

Probing protein aggregation with quartz crystal microbalances.

Knowles TP, Devlin GL, Dobson CM, Welland ME. Knowles TP, et al. Methods Mol Biol. 2011;752:137-45. doi: 10.1007/978-1-60327-223-0_9. Methods Mol Biol. 2011. PMID: 21713635

4

From macroscopic measurements to microscopic mechanisms of protein aggregation.

Cohen SI, Vendruscolo M, Dobson CM, Knowles TP. Cohen SI, et al. J Mol Biol. 2012 Aug 10;421(2-3):160-71. doi: 10.1016/j.jmb.2012.02.031. Epub 2012 Mar 8. J Mol Biol. 2012. PMID: 22406275 Review.

5

Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay.

Arosio P, Cukalevski R, Frohm B, Knowles TP, Linse S. Arosio P, et al. J Am Chem Soc. 2014 Jan 8;136(1):219-25. doi: 10.1021/ja408765u. Epub 2013 Dec 20. J Am Chem Soc. 2014. PMID: 24313551

6

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

Lorenzen N, Nielsen SB, Buell AK, Kaspersen JD, Arosio P, Vad BS, Paslawski W, Christiansen G, Valnickova-Hansen Z, Andreasen M, Enghild JJ, Pedersen JS, Dobson CM, Knowles TP, Otzen DE. Lorenzen N, et al. J Am Chem Soc. 2014 Mar 12;136(10):3859-68. doi: 10.1021/ja411577t. Epub 2014 Feb 28. J Am Chem Soc. 2014. PMID: 24527756

7

Chemical kinetics for drug discovery to combat protein aggregation diseases.

Arosio P, Vendruscolo M, Dobson CM, Knowles TP. Arosio P, et al. Trends Pharmacol Sci. 2014 Mar;35(3):127-35. doi: 10.1016/j.tips.2013.12.005. Epub 2014 Feb 20. Trends Pharmacol Sci. 2014. PMID: 24560688 Review.

8

Density-gradient-free microfluidic centrifugation for analytical and preparative separation of nanoparticles.

Arosio P, Müller T, Mahadevan L, Knowles TP. Arosio P, et al. Nano Lett. 2014 May 14;14(5):2365-71. doi: 10.1021/nl404771g. Epub 2014 Apr 7. Nano Lett. 2014. PMID: 24611748

9

Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.

Månsson C, Arosio P, Hussein R, Kampinga HH, Hashem RM, Boelens WC, Dobson CM, Knowles TP, Linse S, Emanuelsson C. Månsson C, et al. J Biol Chem. 2014 Nov 7;289(45):31066-76. doi: 10.1074/jbc.M114.595124. Epub 2014 Sep 12. J Biol Chem. 2014. PMID: 25217638 Free PMC article.

10

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers.

Cohen SIA, Arosio P, Presto J, Kurudenkandy FR, Biverstal H, Dolfe L, Dunning C, Yang X, Frohm B, Vendruscolo M, Johansson J, Dobson CM, Fisahn A, Knowles TPJ, Linse S. Cohen SIA, et al. Among authors: knowles tpj. Nat Struct Mol Biol. 2015 Mar;22(3):207-213. doi: 10.1038/nsmb.2971. Epub 2015 Feb 16. Nat Struct Mol Biol. 2015. PMID: 25686087 Free PMC article.

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