Chen T - Search Results

1

Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL.

Roberts KG, Yang YL, Payne-Turner D, Lin W, Files JK, Dickerson K, Gu Z, Taunton J, Janke LJ, Chen T, Loh ML, Hunger SP, Mullighan CG. Roberts KG, et al. Among authors: chen t. Blood Adv. 2017 Aug 30;1(20):1657-1671. doi: 10.1182/bloodadvances.2017011296. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296813 Free PMC article.

2

Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells.

Lin W, Wu J, Dong H, Bouck D, Zeng FY, Chen T. Lin W, et al. Among authors: chen t. J Biol Chem. 2008 Nov 7;283(45):30650-7. doi: 10.1074/jbc.M806132200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18784074 Free PMC article.

3

Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.

Dong H, Lin W, Wu J, Chen T. Dong H, et al. Among authors: chen t. BMC Biochem. 2010 Jun 16;11:23. doi: 10.1186/1471-2091-11-23. BMC Biochem. 2010. PMID: 20553580 Free PMC article.

4

Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain.

Leonardi R, Zhang YM, Yun MK, Zhou R, Zeng FY, Lin W, Cui J, Chen T, Rock CO, White SW, Jackowski S. Leonardi R, et al. Among authors: chen t. Chem Biol. 2010 Aug 27;17(8):892-902. doi: 10.1016/j.chembiol.2010.06.006. Chem Biol. 2010. PMID: 20797618 Free PMC article.

5

Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.

Zhao Y, Hammoudeh D, Lin W, Das S, Yun MK, Li Z, Griffith E, Chen T, White SW, Lee RE. Zhao Y, et al. Among authors: chen t. Bioconjug Chem. 2011 Oct 19;22(10):2110-7. doi: 10.1021/bc200346e. Epub 2011 Sep 30. Bioconjug Chem. 2011. PMID: 21916405 Free PMC article.

6

A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor.

Li G, Lin W, Araya JJ, Chen T, Timmermann BN, Guo GL. Li G, et al. Among authors: chen t. Toxicol Appl Pharmacol. 2012 Jan 15;258(2):268-74. doi: 10.1016/j.taap.2011.11.006. Epub 2011 Dec 4. Toxicol Appl Pharmacol. 2012. PMID: 22178739 Free PMC article.

7

Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.

Wang YM, Lin W, Chai SC, Wu J, Ong SS, Schuetz EG, Chen T. Wang YM, et al. Among authors: chen t. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):96-107. doi: 10.1016/j.taap.2013.05.014. Epub 2013 May 22. Toxicol Appl Pharmacol. 2013. PMID: 23707768 Free PMC article.

8

A vinblastine fluorescent probe for pregnane X receptor in a time-resolved fluorescence resonance energy transfer assay.

Lin W, Chen T. Lin W, et al. Among authors: chen t. Anal Biochem. 2013 Dec 15;443(2):252-60. doi: 10.1016/j.ab.2013.09.009. Epub 2013 Sep 14. Anal Biochem. 2013. PMID: 24044991 Free PMC article.

9

Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.

Leung WH, Vong QP, Lin W, Janke L, Chen T, Leung W. Leung WH, et al. Among authors: chen t. J Exp Med. 2013 Nov 18;210(12):2675-92. doi: 10.1084/jem.20122292. Epub 2013 Nov 4. J Exp Med. 2013. PMID: 24190430 Free PMC article.

10

High-throughput screening reveals alsterpaullone, 2-cyanoethyl as a potent p27Kip1 transcriptional inhibitor.

Walters BJ, Lin W, Diao S, Brimble M, Iconaru LI, Dearman J, Goktug A, Chen T, Zuo J. Walters BJ, et al. Among authors: chen t. PLoS One. 2014 Mar 19;9(3):e91173. doi: 10.1371/journal.pone.0091173. eCollection 2014. PLoS One. 2014. PMID: 24646893 Free PMC article.

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