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Postvaccination C-Reactive Protein and C5/gp41732-744 Antibody Level Fold-Changes Over Baseline Are Independent Predictors of Therapeutic HIV Vaccine Effect in a Phase 2 Clinical Study of Vacc-4x.
Huang Y, Zhang L, Jolliffe D, Sanchez B, Stjernholm G, Jelmert Ø, Ökvist M, Sommerfelt MA. Huang Y, et al. Among authors: sommerfelt ma. AIDS Res Hum Retroviruses. 2018 Mar;34(3):307-313. doi: 10.1089/AID.2017.0179. Epub 2018 Feb 13. AIDS Res Hum Retroviruses. 2018. PMID: 29297230 Clinical Trial.
Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: a phase 2 randomised, double-blind, placebo-controlled trial.
Pollard RB, Rockstroh JK, Pantaleo G, Asmuth DM, Peters B, Lazzarin A, Garcia F, Ellefsen K, Podzamczer D, van Lunzen J, Arastéh K, Schürmann D, Clotet B, Hardy WD, Mitsuyasu R, Moyle G, Plettenberg A, Fisher M, Fätkenheuer G, Fischl M, Taiwo B, Baksaas I, Jolliffe D, Persson S, Jelmert O, Hovden AO, Sommerfelt MA, Wendel-Hansen V, Sørensen B. Pollard RB, et al. Among authors: sommerfelt ma. Lancet Infect Dis. 2014 Apr;14(4):291-300. doi: 10.1016/S1473-3099(13)70343-8. Epub 2014 Feb 11. Lancet Infect Dis. 2014. PMID: 24525316 Clinical Trial.
A case for preART-adjusted endpoints in HIV therapeutic vaccine trials.
Huang Y, Zhang L, Jolliffe D, Hovden AO, Ökvist M, Pantaleo G, Sommerfelt MA. Huang Y, et al. Among authors: sommerfelt ma. Vaccine. 2016 Mar 4;34(10):1282-8. doi: 10.1016/j.vaccine.2016.01.025. Epub 2016 Jan 27. Vaccine. 2016. PMID: 26826543 Clinical Trial.
Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial.
Huang Y, Pantaleo G, Tapia G, Sanchez B, Zhang L, Trondsen M, Hovden AO, Pollard R, Rockstroh J, Ökvist M, Sommerfelt MA. Huang Y, et al. Among authors: sommerfelt ma. EBioMedicine. 2017 Oct;24:195-204. doi: 10.1016/j.ebiom.2017.09.028. Epub 2017 Sep 22. EBioMedicine. 2017. PMID: 28970080 Free PMC article. Clinical Trial.
Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption.
Rockstroh JK, Asmuth D, Pantaleo G, Clotet B, Podzamczer D, van Lunzen J, Arastéh K, Mitsuyasu R, Peters B, Silvia N, Jolliffe D, Ökvist M, Krogsgaard K, Sommerfelt MA. Rockstroh JK, et al. Among authors: sommerfelt ma. PLoS One. 2019 Jan 30;14(1):e0210965. doi: 10.1371/journal.pone.0210965. eCollection 2019. PLoS One. 2019. PMID: 30699178 Free PMC article. Clinical Trial.
Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.
Tapia G, Højen JF, Ökvist M, Olesen R, Leth S, Nissen SK, VanBelzen DJ, O'Doherty U, Mørk A, Krogsgaard K, Søgaard OS, Østergaard L, Tolstrup M, Pantaleo G, Sommerfelt MA. Tapia G, et al. Among authors: sommerfelt ma. J Infect. 2017 Dec;75(6):555-571. doi: 10.1016/j.jinf.2017.09.004. Epub 2017 Sep 14. J Infect. 2017. PMID: 28917661 Clinical Trial.
49 results