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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Maynard SE, et al. Among authors: karumanchi sa. J Clin Invest. 2003 Mar;111(5):649-58. doi: 10.1172/JCI17189. J Clin Invest. 2003. PMID: 12618519 Free PMC article.
Soluble endoglin contributes to the pathogenesis of preeclampsia.
Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA. Venkatesha S, et al. Among authors: karumanchi sa. Nat Med. 2006 Jun;12(6):642-9. doi: 10.1038/nm1429. Epub 2006 Jun 4. Nat Med. 2006. PMID: 16751767
Molecular mechanisms of preeclampsia.
Mutter WP, Karumanchi SA. Mutter WP, et al. Among authors: karumanchi sa. Microvasc Res. 2008 Jan;75(1):1-8. doi: 10.1016/j.mvr.2007.04.009. Epub 2007 May 6. Microvasc Res. 2008. PMID: 17553534 Free PMC article. Review.
Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, Maeda N, Karumanchi SA, Smithies O, Takahashi N. Li F, et al. Among authors: karumanchi sa. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13450-13455. doi: 10.1073/pnas.1614947113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821757 Free PMC article.
362 results