Saeed S - Search Results

1

Loss-of-function mutations in ADCY3 cause monogenic severe obesity.

Saeed S, Bonnefond A, Tamanini F, Mirza MU, Manzoor J, Janjua QM, Din SM, Gaitan J, Milochau A, Durand E, Vaillant E, Haseeb A, De Graeve F, Rabearivelo I, Sand O, Queniat G, Boutry R, Schott DA, Ayesha H, Ali M, Khan WI, Butt TA, Rinne T, Stumpel C, Abderrahmani A, Lang J, Arslan M, Froguel P. Saeed S, et al. Nat Genet. 2018 Feb;50(2):175-179. doi: 10.1038/s41588-017-0023-6. Epub 2018 Jan 8. Nat Genet. 2018. PMID: 29311637 Free article.

2

Male offspring of both diabetic parents have higher insulin resistance and serum leptin levels compared to those with one diabetic parent.

Shahid A, Lone KP, Saeed S, Arslan M. Shahid A, et al. Among authors: saeed s. Hormones (Athens). 2008 Oct-Dec;7(4):313-9. doi: 10.14310/horm.2002.1212. Hormones (Athens). 2008. PMID: 19121992 Free article.

3

High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families.

Saeed S, Butt TA, Anwer M, Arslan M, Froguel P. Saeed S, et al. Mol Genet Metab. 2012 May;106(1):121-6. doi: 10.1016/j.ymgme.2012.03.001. Epub 2012 Mar 10. Mol Genet Metab. 2012. PMID: 22463805

4

Changes in levels of peripheral hormones controlling appetite are inconsistent with hyperphagia in leptin-deficient subjects.

Saeed S, Bech PR, Hafeez T, Alam R, Falchi M, Ghatei MA, Bloom SR, Arslan M, Froguel P. Saeed S, et al. Endocrine. 2014 Apr;45(3):401-8. doi: 10.1007/s12020-013-0009-9. Epub 2013 Jul 4. Endocrine. 2014. PMID: 23824601

5

Highly sensitive diagnosis of 43 monogenic forms of diabetes or obesity through one-step PCR-based enrichment in combination with next-generation sequencing.

Bonnefond A, Philippe J, Durand E, Muller J, Saeed S, Arslan M, Martínez R, De Graeve F, Dhennin V, Rabearivelo I, Polak M, Cavé H, Castaño L, Vaxillaire M, Mandel JL, Sand O, Froguel P. Bonnefond A, et al. Among authors: saeed s. Diabetes Care. 2014 Feb;37(2):460-7. doi: 10.2337/dc13-0698. Epub 2013 Sep 16. Diabetes Care. 2014. PMID: 24041679

6

Novel LEPR mutations in obese Pakistani children identified by PCR-based enrichment and next generation sequencing.

Saeed S, Bonnefond A, Manzoor J, Philippe J, Durand E, Arshad M, Sand O, Butt TA, Falchi M, Arslan M, Froguel P. Saeed S, et al. Obesity (Silver Spring). 2014 Apr;22(4):1112-7. doi: 10.1002/oby.20667. Epub 2013 Dec 9. Obesity (Silver Spring). 2014. PMID: 24319006 Free article.

7

Genetic variants in LEP, LEPR, and MC4R explain 30% of severe obesity in children from a consanguineous population.

Saeed S, Bonnefond A, Manzoor J, Shabbir F, Ayesha H, Philippe J, Durand E, Crouch H, Sand O, Ali M, Butt T, Rathore AW, Falchi M, Arslan M, Froguel P. Saeed S, et al. Obesity (Silver Spring). 2015 Aug;23(8):1687-95. doi: 10.1002/oby.21142. Epub 2015 Jul 14. Obesity (Silver Spring). 2015. PMID: 26179253 Free article.

8

Evidence of male hypogonadism at an early age as a familial risk of type 2 diabetes.

Janjua QM, Shahid A, Alam R, Rizwan M, Saeed S, Qazi MH, Arslan M. Janjua QM, et al. Among authors: saeed s. Ann Endocrinol (Paris). 2015 Dec;76(6):658-63. doi: 10.1016/j.ando.2015.10.005. Epub 2015 Nov 27. Ann Endocrinol (Paris). 2015. PMID: 26639184

9

Erratum: Genetic variants in LEP, LEPR, and MC4R explain 30% of severe obesity in children from a consanguineous population.

Saeed S, Bonnefond A, Manzoor J, Shabbir F, Ayesha H, Philippe J, Durand E, Crouch H, Sand O, Ali M, Butt T, Rathore AW, Falchi M, Arslan M, Froguel P. Saeed S, et al. Obesity (Silver Spring). 2017 Apr;25(4):807. doi: 10.1002/oby.21803. Obesity (Silver Spring). 2017. PMID: 28349664 No abstract available.

10

Genetics of Obesity in Consanguineous Populations: Toward Precision Medicine and the Discovery of Novel Obesity Genes.

Saeed S, Arslan M, Froguel P. Saeed S, et al. Obesity (Silver Spring). 2018 Mar;26(3):474-484. doi: 10.1002/oby.22064. Obesity (Silver Spring). 2018. PMID: 29464904 Review.

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