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Combining independent drug classes into superior, synergistically acting hybrid molecules.
Müller-Schiffmann A, März-Berberich J, Andreyeva A, Rönicke R, Bartnik D, Brener O, Kutzsche J, Horn AH, Hellmert M, Polkowska J, Gottmann K, Reymann KG, Funke SA, Nagel-Steger L, Moriscot C, Schoehn G, Sticht H, Willbold D, Schrader T, Korth C. Müller-Schiffmann A, et al. Angew Chem Int Ed Engl. 2010 Nov 8;49(46):8743-6. doi: 10.1002/anie.201004437. Angew Chem Int Ed Engl. 2010. PMID: 20922735 No abstract available.
Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice.
Aileen Funke S, van Groen T, Kadish I, Bartnik D, Nagel-Steger L, Brener O, Sehl T, Batra-Safferling R, Moriscot C, Schoehn G, Horn AH, Müller-Schiffmann A, Korth C, Sticht H, Willbold D. Aileen Funke S, et al. ACS Chem Neurosci. 2010 Sep 15;1(9):639-48. doi: 10.1021/cn100057j. Epub 2010 Aug 2. ACS Chem Neurosci. 2010. PMID: 22778851 Free PMC article.
35 results