Pastukhov O - Search Results

1

Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells.

Vasilakaki S, Pastukhov O, Mavromoustakos T, Huwiler A, Kokotos G. Vasilakaki S, et al. Among authors: pastukhov o. Molecules. 2018 Jan 13;23(1):158. doi: 10.3390/molecules23010158. Molecules. 2018. PMID: 29342835 Free PMC article.

2

Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells.

Vasilakaki S, Barbayianni E, Magrioti V, Pastukhov O, Constantinou-Kokotou V, Huwiler A, Kokotos G. Vasilakaki S, et al. Among authors: pastukhov o. Bioorg Med Chem. 2016 Jul 1;24(13):3029-3034. doi: 10.1016/j.bmc.2016.05.017. Epub 2016 May 13. Bioorg Med Chem. 2016. PMID: 27234891

3

The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells.

Huwiler A, Feuerherm AJ, Sakem B, Pastukhov O, Filipenko I, Nguyen T, Johansen B. Huwiler A, et al. Among authors: pastukhov o. Br J Pharmacol. 2012 Dec;167(8):1691-701. doi: 10.1111/j.1476-5381.2012.02114.x. Br J Pharmacol. 2012. PMID: 22831644 Free PMC article.

4

Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts.

Pastukhov O, Schwalm S, Römer I, Zangemeister-Wittke U, Pfeilschifter J, Huwiler A. Pastukhov O, et al. Cell Physiol Biochem. 2014;34(1):119-33. doi: 10.1159/000362989. Epub 2014 Jun 16. Cell Physiol Biochem. 2014. PMID: 24977486 Free article.

5

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage.

Huwiler A, Kotelevets N, Xin C, Pastukhov O, Pfeilschifter J, Zangemeister-Wittke U. Huwiler A, et al. Among authors: pastukhov o. Br J Pharmacol. 2011 Jan;162(2):532-43. doi: 10.1111/j.1476-5381.2010.01053.x. Br J Pharmacol. 2011. PMID: 20883472 Free PMC article.

6

A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders.

Huwiler A, Bourquin F, Kotelevets N, Pastukhov O, Capitani G, Grütter MG, Zangemeister-Wittke U. Huwiler A, et al. Among authors: pastukhov o. PLoS One. 2011;6(8):e22436. doi: 10.1371/journal.pone.0022436. Epub 2011 Aug 1. PLoS One. 2011. PMID: 21829623 Free PMC article.

7

The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death.

Pastukhov O, Schwalm S, Zangemeister-Wittke U, Fabbro D, Bornancin F, Japtok L, Kleuser B, Pfeilschifter J, Huwiler A. Pastukhov O, et al. Br J Pharmacol. 2014 Dec;171(24):5829-44. doi: 10.1111/bph.12886. Br J Pharmacol. 2014. PMID: 25134723 Free PMC article.

8

High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease.

Meda Spaccamela V, Valencia RG, Pastukhov O, Duppenthaler A, Dettmer MS, Erb J, Steiner UC, Hillinger S, Speckmann C, Ehl S, Reichenbach J, Siler U. Meda Spaccamela V, et al. Among authors: pastukhov o. Front Immunol. 2019 Oct 18;10:2236. doi: 10.3389/fimmu.2019.02236. eCollection 2019. Front Immunol. 2019. PMID: 31681257 Free PMC article. Clinical Trial.

9

Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis.

Siler U, Romao S, Tejera E, Pastukhov O, Kuzmenko E, Valencia RG, Meda Spaccamela V, Belohradsky BH, Speer O, Schmugge M, Kohne E, Hoenig M, Freihorst J, Schulz AS, Reichenbach J. Siler U, et al. Among authors: pastukhov o. J Allergy Clin Immunol. 2017 Jan;139(1):212-219.e3. doi: 10.1016/j.jaci.2016.04.041. Epub 2016 Jul 22. J Allergy Clin Immunol. 2017. PMID: 27458052

10

Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction.

Moens L, Gouwy M, Bosch B, Pastukhov O, Nieto-Patlàn A, Siler U, Bucciol G, Mekahli D, Vermeulen F, Desmet L, Maebe S, Flipts H, Corveleyn A, Moshous D, Philippet P, Tangye SG, Boisson B, Casanova JL, Florkin B, Struyf S, Reichenbach J, Bustamante J, Notarangelo LD, Meyts I. Moens L, et al. Among authors: pastukhov o. J Clin Immunol. 2019 Apr;39(3):298-308. doi: 10.1007/s10875-019-00603-w. Epub 2019 Mar 5. J Clin Immunol. 2019. PMID: 30838481 Free PMC article.

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