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Page 1
Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.
Sivro A, Schuetz A, Sheward D, Joag V, Yegorov S, Liebenberg LJ, Yende-Zuma N, Stalker A, Mwatelah RS, Selhorst P, Garrett N, Samsunder N, Balgobin A, Nawaz F, Cicala C, Arthos J, Fauci AS, Anzala AO, Kimani J, Bagaya BS, Kiwanuka N, Williamson C, Kaul R, Passmore JS, Phanuphak N, Ananworanich J, Ansari A, Abdool Karim Q, Abdool Karim SS, McKinnon LR; CAPRISA004 and RV254 study groups. Sivro A, et al. Among authors: ansari a. Sci Transl Med. 2018 Jan 24;10(425):eaam6354. doi: 10.1126/scitranslmed.aam6354. Sci Transl Med. 2018. PMID: 29367348 Free PMC article.
Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.
Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, Villinger T, Little D, Parslow TG, Santangelo PJ, Villinger F, Fauci AS, Ansari AA. Byrareddy SN, et al. Among authors: ansari aa. Nat Med. 2014 Dec;20(12):1397-400. doi: 10.1038/nm.3715. Epub 2014 Nov 24. Nat Med. 2014. PMID: 25419708 Free PMC article.
Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates.
Byrareddy SN, Sidell N, Arthos J, Cicala C, Zhao C, Little DM, Dunbar P, Yang GX, Pierzchalski K, Kane MA, Mayne AE, Song B, Soares MA, Villinger F, Fauci AS, Ansari AA. Byrareddy SN, et al. Among authors: ansari aa. J Immunol. 2015 Jun 15;194(12):5968-79. doi: 10.4049/jimmunol.1402866. Epub 2015 May 6. J Immunol. 2015. PMID: 25948815 Free PMC article.
Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy.
Byrareddy SN, Arthos J, Cicala C, Villinger F, Ortiz KT, Little D, Sidell N, Kane MA, Yu J, Jones JW, Santangelo PJ, Zurla C, McKinnon LR, Arnold KB, Woody CE, Walter L, Roos C, Noll A, Van Ryk D, Jelicic K, Cimbro R, Gumber S, Reid MD, Adsay V, Amancha PK, Mayne AE, Parslow TG, Fauci AS, Ansari AA. Byrareddy SN, et al. Among authors: ansari aa. Science. 2016 Oct 14;354(6309):197-202. doi: 10.1126/science.aag1276. Science. 2016. PMID: 27738167 Free PMC article.
The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.
McGary CS, Alvarez X, Harrington S, Cervasi B, Ryan ES, Iriele RI, Paganini S, Harper JL, Easley K, Silvestri G, Ansari AA, Lichterfeld M, Micci L, Paiardini M. McGary CS, et al. Among authors: ansari aa. Mucosal Immunol. 2017 Jul;10(4):1082-1096. doi: 10.1038/mi.2016.116. Epub 2017 Jan 4. Mucosal Immunol. 2017. PMID: 28051083 Free PMC article.
2,558 results