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An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. Schrade K, et al. Among authors: elkins jm. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PLoS One. 2018. PMID: 29373579 Free PMC article.
Structure of dystrophia myotonica protein kinase.
Elkins JM, Amos A, Niesen FH, Pike AC, Fedorov O, Knapp S. Elkins JM, et al. Protein Sci. 2009 Apr;18(4):782-91. doi: 10.1002/pro.82. Protein Sci. 2009. PMID: 19309729 Free PMC article.
Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions.
Schäfer G, Milić J, Eldahshan A, Götz F, Zühlke K, Schillinger C, Kreuchwig A, Elkins JM, Abdul Azeez KR, Oder A, Moutty MC, Masada N, Beerbaum M, Schlegel B, Niquet S, Schmieder P, Krause G, von Kries JP, Cooper DM, Knapp S, Rademann J, Rosenthal W, Klussmann E. Schäfer G, et al. Among authors: elkins jm. Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12187-91. doi: 10.1002/anie.201304686. Epub 2013 Sep 23. Angew Chem Int Ed Engl. 2013. PMID: 24115519 Free PMC article. No abstract available.
The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex.
Abdul Azeez KR, Knapp S, Fernandes JM, Klussmann E, Elkins JM. Abdul Azeez KR, et al. Among authors: elkins jm. Biochem J. 2014 Dec 1;464(2):231-9. doi: 10.1042/BJ20140606. Biochem J. 2014. PMID: 25186459 Free PMC article.
138 results